Sort By:

How Immune Cells From Blood Beget Aging in Brain

CONFERENCE COVERAGE 2018-12-14 Conference Coverage Never mind the wrinkles and gray hair. Embattled microglia, waning neurogenesis, and withering synapses are also part and parcel of the aging process. What drives those seemingly inexorable changes inside the brain? At the Society for ...

Autopsy Study Confirms Flortaucipir PET Lights Up Tau Pathology

RESEARCH NEWS 2018-12-14 Research News For a PET ligand, validation is literally a matter of life and death. Its reliability rides on a direct comparison of tracer uptake in a living person with his or her autopsy result. In the December 3 JAMA Neurology, Ruben Smith and Oskar ...

Microglia Reveal Formidable Complexity, Deep Culpability in AD

RESEARCH NEWS 2018-12-13 Research News Genetic studies of late-onset Alzheimer’s point to variations in the function of the innate immune system—and its CNS cadre, the microglia. Why would immune genes determine whether a person will get the disease? Perhaps because the innate ...

World Dementia Council Takes Stock of Progress, Challenges

CONFERENCE COVERAGE 2018-12-12 Conference Coverage On December 5, global leaders came together at the Wellcome Trust offices in London for a meeting of the World Dementia Council, the body charged with leading the global response to dementia and coordinating international efforts ...

Does Oleic Acid Hold the Key to α-Synuclein Toxicity?

RESEARCH NEWS 2018-12-10 Research News Dieticians recommend consuming mostly unsaturated fats for cardiovascular health and a slim waistline. Now, in a surprising twist, researchers claim one such fat, oleic acid, may worsen α-synuclein pathology. In the December 4 Molecular Cell ...

First Round of Awards from Chan Zuckerberg Initiative Announced

COMMUNITY NEWS 2018-12-07 Community News Earlier this year, the Chan Zuckerberg Initiative (CZI) dove into the field of neurodegenerative disease research, launching the Neurodegenerative Challenge Network to promote cross-disciplinary basic science research (Feb 2018 news). On ...

Neurofilament Light: A Universal Mark of Neurodegeneration

RESEARCH NEWS 2018-12-07 Research News A paper in the December 3 JAMA Neurology adds yet more evidence that neurofilament light (NfL) protein is a general biomarker of neurodegeneration. Scientists led by Bob Olsson and Erik Portelius, University of Gothenburg, Sweden, found ...

A Proteomics Dive into Cause of Frontotemporal Dementia

CONFERENCE COVERAGE 2018-12-06 Conference Coverage If DNA makes RNA makes protein, then genomic variants make RNA make protein … make disease. While scientists have found polymorphisms that associate with various forms of frontotemporal dementia, deciphering how they perturb proteins ...

Tracking Onset and Progression of Frontotemporal Dementia

CONFERENCE COVERAGE 2018-12-05 Conference Coverage Now that initiatives such as ARTFL and LEFFTDS have gathered sufficient numbers of participants for scientists to tackle prevention and treatment trials (see Part 2 of this conference series), the need for better tools to track onset ...

Natural History Studies Provide Foundation for FTD Research

CONFERENCE COVERAGE 2018-12-05 Conference Coverage At the 11th International Congress on Frontotemporal Dementia, held November 11–14 in Sydney, no two acronyms were heard more than ARTFL and LEFFTDS. For those readers who have not built them into their FTD vocabulary yet, Advancing ...

11th ICFTD Meeting in Sydney Sorts Out Clinical Subtypes

CONFERENCE COVERAGE 2018-12-04 Conference Coverage Indigenous Australian people opened the 11th International Conference on Frontotemporal Dementia at the International Convention Center, Sydney, November 11–14. Koomurri performers welcomed more than 600 attendees from 37 countries. ...

Going the Distance: FUS Travels to Terminals, Drops Off RNA

CONFERENCE COVERAGE 2018-12-02 Conference Coverage Following their transcription from the genome, RNA messages exit the nucleus and enter the cytoplasm, sometimes traveling vast distances before they are finally translated into protein. RNA-binding proteins are helping hands on this ...

Beyond the Nucleus: TDP-43 Sticks Together, For Better or Worse

CONFERENCE COVERAGE 2018-12-01 Conference Coverage Similar to a newborn human, nascent RNA transcripts need a lot of coddling before they realize their purpose in life (that is, translation into protein). It takes a village of RNA-binding proteins to accomplish this. They see to the ...

Current Filters

  • TYPE: News x

Remove all filters

Filter By

  • All
  • Past 7 Days
  • Past 30 Days
  • Past 90 Days
  • Past 12 Months
  • Specific Dates
    1. From