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Could Rogue APP Variants Invade Genome of Individual Neurons?

RESEARCH NEWS 2018-11-21 Research News Multiple copies of the amyloid precursor gene crop up in adult neurons of the human brain, creating a heterogeneous neuronal landscape in a single person. This is especially true in brains from people with sporadic Alzheimer’s disease, but ...

Trial-Ready Cohorts Take Shape in Europe and U.S.

CONFERENCE COVERAGE 2018-11-20 Conference Coverage To speed up recruitment into Alzheimer’s trials, researchers have created innovative new platforms that establish trial-ready cohorts of people at early disease stages. The farthest along is the European Prevention of Alzheimer’s ...

Trials of Diabetes-Related Therapies: Mainly a Bust

CONFERENCE COVERAGE 2018-11-20 Conference Coverage This is Part 2 of a two-part story. Click here for Part 1. The highs and lows of diabetes-related therapies were on display at the Clinical Trials on Alzheimer’s Disease Conference, held October 24–27 in Barcelona, Spain. This time ...

Fits and Starts: Trial Results from the CTAD Conference

CONFERENCE COVERAGE 2018-11-20 Conference Coverage This is Part 1 of a two-part story. Click here for Part 2. As in years past, trial results offered up a mixed bag of goods and duds at the Clinical Trials on Alzheimer’s Disease Conference, held October 24–27 in Barcelona, Spain. In ...

How Does The NIA-AA Framework Measure Up Against Real Data?

CONFERENCE COVERAGE 2018-11-19 Conference Coverage This past spring, the National Institute on Aging and Alzheimer’s Association proposed a new research framework in an effort to nudge the field toward a biological definition of Alzheimer’s disease (Apr 2018 news). The framework ...

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