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Neuronal SRPX2 Spoils Microglial Appetite for Synapses

RESEARCH NEWS 2020-07-24 Research News For better or worse, complement proteins tag synapses for elimination by microglia. A paper published July 13 in Nature Neuroscience identifies a neuronal protein that keeps this process in check. Researchers led by Gek-Ming Sia at the ...

Rogue APP Claim Embroiled in Contamination Concerns

RESEARCH NEWS 2020-07-17 Research News It sounded wild at the time: A Nature paper uncovered multiple copies of APP inserted into neuronal genomes, especially among people with sporadic AD. These interlopers purportedly derived from APP mRNA transcripts, which had been reverse ...

Does Huntington’s Disease Begin in the Womb?

RESEARCH NEWS 2020-07-17 Research News Huntington’s disease, like most neurodegenerative conditions, strikes adults. Yet children who carry the infamous causative triple repeat expansion have slightly smaller brains than noncarriers even while they are as functional as their ...

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