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Can BACE2 Protect Against Amyloidosis?

RESEARCH NEWS 2020-02-18 Research News It may seem counterintuitive, but could BACE2 protect against amyloidosis, rather than contribute to it? This is the central question in a manuscript posted to bioRxiv. Non-amyloidogenic processing of APP, and Aβ peptides, by BACE2 may ...

CryoEM of CBD Tau Suggests Another Unique Protofibril

RESEARCH NEWS 2020-02-14 Research News Evidence continues to pile up that filaments of aggregated tau form unique strains in different tauopathies. Why is that? A paper published online in Cell on February 6 suggests that post-translational modifications help decide a filament’s ...

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