44 RESULTS
COMMUNITY NEWS 2019-12-23 Community News Continuing a steady climb in funding for Alzheimer’s research, the Senate approved a $350 million increase in funding for Alzheimer’s and dementia research at the National Institutes of Health for the 2020 fiscal year. The appropriation bil
CONFERENCE COVERAGE 2019-12-21 Conference Coverage For therapies taking aim at Alzheimer’s disease, exerting an effect in the brain seems critical. And obvious. But according to results on display at 12th Clinical Trials on Alzheimer’s Disease conference, held December 4–7 in San Diego
CONFERENCE COVERAGE 2019-12-20 Conference Coverage Anti-amyloid antibodies are at long last showing promise for treating Alzheimer’s disease, but for long-term use, researchers are seeking cheaper and easier options than monthly infusions. They want that elusive once-a-day pill. BACE i
CONFERENCE COVERAGE 2019-12-20 Conference Coverage With aducanumab’s resurrection driving renewed interest in anti-amyloid antibody therapies, researchers at the 12th Clinical Trials on Alzheimer’s Disease conference, held December 4–7 in San Diego, happily provided updates on their ow
CONFERENCE COVERAGE 2019-12-19 Conference Coverage While a suite of new CSF markers has entered a mature stage where they get validated with identical methods in large international cohorts (see previous CTAD story), much newer blood tests are catching up fast. Scientists are pushing t
CONFERENCE COVERAGE 2019-12-19 Conference Coverage CSF Aβ42 and phospho-tau may remain the quintessential fluid Alzheimer’s disease biomarkers for now, but a growing cadre of other markers are also proving their worth. At the Clinical Trials on Alzheimer’s Disease conference, held Dece
CONFERENCE COVERAGE 2019-12-13 Conference Coverage There was a new feeling in the air at the 12th Clinical Trials on Alzheimer’s Disease conference. It felt good: After decades of failure, the field might finally be turning a corner. The renewed optimism at the meeting, held December 4
RESEARCH NEWS 2019-12-13 Research News To ensure homeostasis in the brain, microglia are constantly feeling about with their finger-like processes, making sure that all is well, or sensing problems and rearing up to help. A study in today’s Science suggests that these processes d
RESEARCH NEWS 2019-12-13 Research News Biogen announced today that its anti-tau passive immunotherapy, gosuranemab, had failed to pass muster in a Phase 2 trial for people with progressive supranuclear palsy. Biogen will continue testing the immunotherapy in the Phase 2 TANGO tri
RESEARCH NEWS 2019-12-06 Research News In back-to-back papers in the December 4 Science Translational Medicine, scientists led by Daniela Kaufer, University of California, Berkeley, and Alon Friedman, Ben-Gurion University of the Negev, Beer-Sheva, Israel, report that age-related
RESEARCH NEWS 2019-12-05 Research News Gene therapy has re-emerged as a potentially revolutionary treatment for familial and, eventually, sporadic, Alzheimer’s disease (Parts 2 and 3 of the Society for Neuroscience 2019 annual meeting series). While researchers are mulling over t
CONFERENCE COVERAGE 2019-11-28 Conference Coverage Buoyed by success in spinal muscular atrophy, scientists are once again devising gene-based therapies for neurodegeneration. Some are permanent, which makes proving their safety all the more challenging. Still, as shown at this year’s
CONFERENCE COVERAGE 2019-11-27 Conference Coverage Twenty years ago, researchers took fibroblasts from the skin of eight Alzheimer’s patients, engineered them to produce nerve-growth factor, and slid them into each volunteer’s basal forebrain. They hoped the neurotrophin would halt or
RESEARCH NEWS 2019-11-26 Research News Most studies of gene-expression changes in Alzheimer’s brain analyze tissue samples containing a mix of different cell types. This makes it impossible to definitively figure out the contribution of specific cells. In the November 25 Nature N
