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RESEARCH NEWS 2019-04-10 Research News Groups of neurons fire in sync with each other across the brain when it performs a task; however, with age, they fall out of step. In the April 8 Nature Neuroscience, Robert Reinhart and John Nguyen of Boston University reported that out-of-
RESEARCH NEWS 2019-04-05 Research News As if the biological functions of membrane-bound TREM2 weren’t complicated enough, researchers also have to contend with the actions of its freewheeling counterpart, soluble TREM2. In the March 25 Nature Communications, researchers led by Gu
RESEARCH NEWS 2019-04-05 Research News As researchers are becoming wise to microglial diversity, they may also want to keep their eyes out for varied populations of the true glia of the brain. In the April 1 Nature Neuroscience, Jeffrey Rothstein’s group at Johns Hopkins Universi
RESEARCH NEWS 2019-04-05 Research News Microglia tend to get off-kilter in Alzheimer’s and other neurodegenerative diseases. Now, researchers in Tony Wyss-Coray’s lab at Stanford University believe they have discovered a means of restoring their homeostasis. On April 3 in Nature
RESEARCH NEWS 2019-04-03 Research News Results of the Imaging Dementia–Evidence for Amyloid Scanning study were published April 2 in JAMA. IDEAS tested if amyloid PET affected the management or outcomes of dementia care. As reported previously on Alzforum, physicians changed thei
RESEARCH NEWS 2019-03-29 Research News In the latest attempt to rid neurons of toxic tau, researchers are trying to harness and improve cells’ own clearance mechanisms. Researchers led by Kenneth Kosik, University of California, Santa Barbara, used a small molecule called lonafar
RESEARCH NEWS 2019-03-29 Research News Women with shorter-than-average reproductive periods are at a markedly increased risk for dementia, according to a paper published March 27 in Neurology. Researchers led by Paola Gilsanz at Kaiser Permanente Division of Research in Oakland a
RESEARCH NEWS 2019-03-27 Research News An advisory panel appointed by the FDA was nearly unanimous in recommending yesterday that Yokneam, Israel-based Neuronix not be allowed to market its neuroAD Therapy System in the U.S. Approved for AD in Europe, Australia, and Israel, the d
RESEARCH NEWS 2019-03-25 Research News Does Alzheimer’s disease retard the birth of new neurons in the hippocampus? Data from mouse models suggests it might, but evidence from human brain has been lacking. In today’s Nature Medicine, researchers led by María Llorens-Martín at the
RESEARCH NEWS 2019-03-22 Research News Scientists have known for years that the common H1 haplotype of the tau gene MAPT somehow raises a person’s risk of the rare neurodegenerative disorder progressive supranuclear palsy (PSP). It does so by more than fivefold, similar to what A
COMMUNITY NEWS 2019-03-22 Community News The 2019 Potamkin Prize for Research in Pick’s, Alzheimer’s and Related Diseases goes to Randall Bateman, Washington University, St. Louis. Bateman is being recognized for his work on the underlying biology of AD and for his commitment to f
CONFERENCE COVERAGE 2019-03-22 Conference Coverage A busy hub of subcommittee meetings and brainstorming sessions, the Alzheimer's Disease-Related Dementias Summit 2019, held March 14–15 at the National Institutes of Health, Bethesda, Maryland, articulated research priorities for
CONFERENCE COVERAGE 2019-03-22 Conference Coverage In their grand project to hasten the start-up of therapy trials, the Global Alzheimer’s Platform trial network (GAP-Net) is looking to unclog procedural bottlenecks. Part 1 of this report of the GAP-Net Site Optimization conference, he
CONFERENCE COVERAGE 2019-03-21 Conference Coverage Outside the daffodils and forsythia were blooming, but the group assembled in Nashville, Tennessee, hardly took notice. At the GAP-Net Site Optimization Conference, held February 27–March 1, representatives of 61 academic and private c
RESEARCH NEWS 2019-03-21 Research News Whether sustained on the field or in the ring, repeated blows to the head result in a distinctive strain of tau filaments in the brain. In the March 20 Nature, researchers led by Sjors Scheres and Michel Goedert of the MRC Laboratory of Mole
