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RESEARCH NEWS 2003-05-16 Research News Back-to-back papers in today’s Science shed new light on the role that insulin and heat shock proteins may play in the aging process. Gerald Shulman and colleagues at Yale University School of Medicine report that mitochondrial dysfunction m
RESEARCH NEWS 2003-05-15 Research News Papers in tomorrow’s Cell and last week's Neuron reveal that protein phosphorylation plays a key role in spinocerebellar ataxia type 1 (SCA-1), an ultimately fatal neurodegenerative disease marked by progressive loss of muscle control.
RESEARCH NEWS 2003-05-13 Research News A paper in yesterday’s online Nature Medicine suggests that the involuntary movements that accompany standard treatment for Parkinson's disease may be controlled by administration of neurotransmitter analogs that bind to a particular su
RESEARCH NEWS 2003-05-09 Research News A report in next week's PNAS adds to the growing evidence that insulin-degrading enzyme (IDE), or insulysin, plays a role in the degradation of amyloid-β (Aβ). For some time now, IDE has been touted as a possible risk factor for late-on
RESEARCH NEWS 2003-05-09 Research News On May 4-5, Harvard Medical School briefed reporters on new directions in biomedical research. The meeting featured diverse presentations ranging from basic research on RNA splicing and clinical trials of proteasome inhibitors to the evoluti
CONFERENCE COVERAGE 2003-05-06 Conference Coverage Successful radiotracers for positron emission tomography (PET) diagnosis of AD are a mere year or two away, according to leading researchers who met on May 1-2 in New York. The real challenge now will be in convincing the Food and Drug
RESEARCH NEWS 2003-05-02 Research News In today's Science, researchers report that mutations in the protein dynein-the motor that drives the transport of large molecules from the synaptic terminal back to the neuron’s cell body-can lead to forms of neurodegeneration reminisc
RESEARCH NEWS 2003-05-02 Research News Neuronal progenitors are faced with many forks on the road to becoming one of more than 1,000 different neurons found in the human central nervous system. Tracking exactly what pathways progenitors take to become a specific type of neuron ha
RESEARCH NEWS 2003-05-01 Research News Counterintuitive as it may seem, in tomorrow's Science researchers report that the inhibitory neurotransmitter ã-aminobutyric acid (GABA) can temporarily restore age-related losses of visual acuity in monkeys. Audie Leventhal, Universit
RESEARCH NEWS 2003-04-27 Research News In this week's Journal of the American Medical Association, researchers report a correlation between Alzheimer's disease (AD) and the appearance in the cerebrospinal fluid (CSF) of two proteins thought to play major roles in the pr
RESEARCH NEWS 2003-04-27 Research News Several anticholesterol drugs, particularly statins, at standard doses can significantly reduce plasma levels of the brain cholesterol degradation product 24S-hydrocholesterol, according to a report in this week's Archives of Neurology.
COMMUNITY NEWS 2003-04-27 Community News Massimo Tabaton of the University of Genoa, Italy, has been awarded this year's Alzheimer's Medal. The award is presented annually by the associate editors of the Journal of Alzheimer's Disease "for the best article publ
RESEARCH NEWS 2003-04-24 Research News There is growing interest in the overlap among Alzheimer's disease, Parkinson's disease, and less common synucleinopathies and tauopathies that can share features of both diseases. Two current papers looking at different levels of
RESEARCH NEWS 2003-04-18 Research News Like good cholesterol and bad cholesterol, the Alzheimer's community has realized that there may also be good Aβ and bad Aβ. What if an antibody was developed to target only the latter? A tall order, yet scientists from the University o
RESEARCH NEWS 2003-04-17 Research News Stem cells injected into the cerebral ventricles-or even injected intravenously-find their way to sites of inflammation in an animal model of multiple sclerosis (MS), according to a report in today’s Nature. Once there, they replace the dama
