6120 RESULTS
RESEARCH NEWS 2003-08-09 Research News Contentions that activation of the cell cycle and apoptosis at least partly underlie the neurodegeneration seen in Alzheimer's disease (AD) have slowly gained experimental support (see ARF related news story, ARF live discussion, and AR
RESEARCH NEWS 2003-08-06 Research News The prolyl isomerase Pin1 protects against tau-mediated, age-dependent neurodegeneration, according to a study in the July 31 Nature. Kun Ping Lu, at Harvard Medical School, and his colleagues combine human postmortem data in AD brains with
RESEARCH NEWS 2003-08-04 Research News As the old saying goes, "An ounce of prevention is worth a pound of cure." If that's an ounce of a nonsteroidal antiinflammatory drug (NSAID), then the sages may have gotten it right, because despite evidence that NSAIDS do li
RESEARCH NEWS 2003-07-30 Research News Bored with the same old foods you tend to eat? Consider adding more fish and some specific plant products. Two recent studies suggest that not only would this liven up your diet, but it might also lower risk of developing Alzheimer's di
RESEARCH NEWS 2003-07-30 Research News Parkinson's patients who take medications that block muscarinic cholinergic receptors have increased amyloid plaque and neurofibrillary tangle pathology, according to an article by Elaine Perry of the Newcastle General Hospital in Engla
RESEARCH NEWS 2003-07-24 Research News In the July 8 issue of Current Biology, researchers at the University of California, Los Angeles, and Kyoto University, Japan, reveal that mice carrying a mutated version of the Notch gene suffer from spatial learning and memory defects. The
RESEARCH NEWS 2003-07-21 Research News It’s getting hot around calcium. A trend is afoot about something going awry with calcium regulation in Alzheimer neurons, and it makes this ion an increasingly attractive suspect in AD pathogenesis, even if important details remain murky. T
RESEARCH NEWS 2003-07-21 Research News Some foods only reveal their flavor after you add a dash of salt. Similarly, say the authors of an article in the July 18 issue of Science, some genes only show an association with disease when environmental factors are taken into account. T
RESEARCH NEWS 2003-07-20 Research News The proteasome, that large subcellular grinder that recycles protein, plays a major role in localized degeneration of axons, according to a report in this week's Neuron. Such neuronal damage typically follows traumatic injury, but it ca
CONFERENCE COVERAGE 2003-07-20 Conference Coverage On May 29 and 30, the New York City-based Institute for the Study of Aging convened a small symposium to take the pulse of current research on ApoE, the leading risk factor for nonfamilial AD. The gathered scientists were charged parti
RESEARCH NEWS 2003-07-20 Research News In this week’s Neuron, researchers report that polyglutamine-expanded huntingtin (Htt)—the direct cause of Huntington's disease—exacerbates inositol triphosphate-mediated calcium signaling. The paper's principal. author, Ilya Bezpr
RESEARCH NEWS 2003-07-20 Research News Human tau-whether normal or a disease-causing mutant-does not make for a healthy C. elegans. In the Early Edition of PNAS, Gerry Schellenberg and colleagues report that both types of transgenic tau lead to behavioral, synaptic, and pathologi
RESEARCH NEWS 2003-07-20 Research News Tao et al. and Honbou et al. recently reported the crystal structure of DJ-1 at resolutions of 1.8 and 1.95 Ångstroms, respectively (see ARF related news story), but the latest report by Greg Petsko and colleagues in the July 10 PNAS Early E
RESEARCH NEWS 2003-07-14 Research News A report in this week's PNAS suggests that neurogenesis can occur in response to neurodegeneration in human brains. Principal author Richard Faull and colleagues at the University of Auckland, New Zealand, report that significantly more
RESEARCH NEWS 2003-07-11 Research News Recent evidence has enhanced the image of astrocytes, suggesting these glial cells are a source for stem cells (see ARF related news story), and that they mop up Aβ (see ARF related news story). But online publications in this week's PN
