RESEARCH NEWS 2003-07-08 Research News Just grind some dehydrated blueberries into your people-chow and counteract the effects of aging and Alzheimer's disease on memory. That's one hypothesis we can take away from a recent study by Jim Joseph and colleagues, wherein th
RESEARCH NEWS 2003-07-08 Research News In Alzheimer's disease (AD), the first significant damage to neurons may be the loss of proteins involved in long-term potentiation (LTP) and memory. So conclude Dave Morgan and colleagues from the University of South Florida, Tampa, an
CONFERENCE COVERAGE 2003-07-03 Conference Coverage The 9th annual meeting of the Organization for Human Brain Mapping was held from June 18-22 in New York City. Over 2,000 attendants escaped the rain to absorb workshops, symposia, and posters covering everything from the physics of ima
RESEARCH NEWS 2003-07-03 Research News Synapses-those specialized junctions that facilitate transmission of action potentials between neurons-are composed of a myriad of highly sophisticated proteins. Some, like neurexins, have yet to be fully characterized. In recent issues of N
RESEARCH NEWS 2003-07-01 Research News In this month's Nature Cell Biology,Frank Lezoualc'h and colleagues at the University of South Paris report that serotonin, or 5-hydroxy tryptamine (5HT), mediates sAPPα release through a cyclic AMP (cAMP) signaling pathway indepen
INTERVIEWS 2003-06-26 Interviews Vincent Marchesi Alzforum scientific advisor Vincent Marchesi is currently director of the Boyer Center of Molecular Medicine at Yale University School of Medicine. When his wife, a doctor herself, was diagnosed with Alzheimer's Disease ei
RESEARCH NEWS 2003-06-26 Research News In the 24 June PNAS Early Edition, researchers report that a biologically ancient defense mechanism for ridding the central nervous system (CNS) of invading pathogens also damages neurons. Part of the innate immune system, this defense mecha
RESEARCH NEWS 2003-06-26 Research News Soon after the World Health Organization bestowed its approval on the protein 14-3-3 as an important diagnostic marker for sporadic Creutzfeldt-Jakob disease (sCJD), reports began to come in that its sensitivity and specificity might not be
RESEARCH NEWS 2003-06-20 Research News Papers in press in the Journal of Biological Chemistry and PNAS explore the relationship between Alzheimer's disease (AD) and nicotine. In the June 11 JBC Papers in Press, principal author Daniel Lee and colleagues at Biogen Inc., Cambr
RESEARCH NEWS 2003-06-20 Research News The U.S. Food and Drug Administration has given approval for the drug Stalevo-a cocktail of levodopa (L-dopa), carbidopa, and entacapone-to be marketed in the United States for the treatment of Parkinson's disease, according to a press
RESEARCH NEWS 2003-06-19 Research News The blood-brain barrier (BBB) is cropping up with increasing frequency in discussions of Alzheimer's disease therapy. It is an ever-present concern for researchers hoping to introduce therapies-whether drugs, a vaccine, or stem cells-to
RESEARCH NEWS 2003-06-17 Research News The not-for-profit Amyotrophic Lateral Sclerosis-Therapy Development Foundation (ALS-TDF), based in Newton, Massachusetts, has entered into a collaboration with University of Chicago stem cell researcher Kimonobu Sugaya. Announced last week,
RESEARCH NEWS 2003-06-13 Research News Two in-press papers in the Journal of Biological Chemistry reveal the crystal structure of DJ-1, a protein of unknown function that was recently implicated in the etiology of familial Parkinson's disease (see ARF related news story). Wo
RESEARCH NEWS 2003-06-12 Research News In last week's PNAS online, researchers reported that murine embryonic stem cells exposed to pyrrolpyrimidines differentiate into neurons. This result raises hope that the fate of stem cells in vivo may one day be controlled by the use
CONFERENCE COVERAGE 2003-06-09 Conference Coverage Are you intrigued by the rapidly unfolding progress of basic RNAi research? Do you wonder how early attempts to develop therapeutics out of this field are shaping up, and where the technical barriers lie? If so, you might enjoy an onli