6124 RESULTS
RESEARCH NEWS 2004-01-22 Research News Combining memantine with an older, widely used AD drug further improves measures of cognition, global well-being, activities of daily living, and behavior in people with moderate to severe AD, according to a study published in the January 21
RESEARCH NEWS 2004-01-22 Research News What if all it took was a little sugar—not to make some other medicine go down, but as a therapy in itself for Huntington's disease? This is the promise of an article published online January 18 in Nature Medicine. Nobuyuki Nukina and h
RESEARCH NEWS 2004-01-21 Research News For several years now, the Alzheimer's research and treatment communities have been awaiting the fruition of promising research into quantitative imaging agents that could signal the presence of amyloid in the brains of living people (s
RESEARCH NEWS 2004-01-18 Research News What exactly distinguishes an old cell from a new one? Telomeres may be shorter, but for the most part, the genome hasn't changed. The cell’s collective protein supply, or proteome, is another matter, however. Anyone interested in study
RESEARCH NEWS 2004-01-16 Research News What to use to make a good raft? This question has been debated since long before Robinson Crusoe, but if it’s lipid rafts we are talking about, you may want to shy away from using sphingolipids. A paper in press in the Journal of Biological
CONFERENCE COVERAGE 2004-01-13 Conference Coverage This report summarizes some of the genetic findings for late-onset Alzheimer's disease presented last November at the 33rd Annual Meeting of the Society for Neuroscience in New Orleans. It covers recent progress in identifying the
RESEARCH NEWS 2004-01-12 Research News In the current issue of Science, Anirvan Ghosh and colleagues at Johns Hopkins University report that CREST—a protein that interacts with CREB (cAMP response element-binding protein) binding protein, or CBP—is required for proper dendritic g
RESEARCH NEWS 2004-01-09 Research News Also see Q&A below with Masuo Ohno, Robert Vassar, and John Disterhoft. In yesterday’s Neuron, researchers presented fresh in-vivo support for the amyloid hypothesis, and they bolster the status of the APP protease BACE as the current fa
RESEARCH NEWS 2004-01-03 Research News Genome, transcriptome, proteome, and now we have the interactome, the full complement of protein-protein interactions that can occur in the cell. Marc Vidal and colleagues from the Dana-Farber Cancer Institute, Boston, and numerous other res
RESEARCH NEWS 2004-01-03 Research News Results are in from the first pilot study to test the potential benefit of clioquinol in Alzheimer's disease (AD) patients, suggesting that the drug improves cognition and lowers plasma levels of Aβ42 in some patients. Expanding on thei
RESEARCH NEWS 2004-01-03 Research News Localized gene transfer has produced the first rat model of neurofibrillary tangles, announce the authors of a report in the January 2004 American Journal of Pathology. The researchers, led by Ron Klein of Louisiana State University Health S
RESEARCH NEWS 2003-12-30 Research News Two recent studies confirm that local inflammation inhibits adult neurogenesis in the hippocampus and, in a promising advance, they find evidence that systemic administration of common nonsteroidal antiinflammatory drugs (NSAIDs) can restore
RESEARCH NEWS 2003-12-26 Research News As government officials scramble to contain the current scare over a cow that tested positive for BSE in Washington state earlier this week, researchers in New York and Boston report that experiments with slugs and yeast suggest prion-like b
RESEARCH NEWS 2003-12-26 Research News A report in last week's Cell suggests that TGF-β1, one of the three mammalian isoforms of that growth factor, can protect against excitotoxic neurodegeneration, which is thought to be related to the pathogenesis of several diseases incl
CONFERENCE COVERAGE 2003-12-24 Conference Coverage Scientists prospecting the amyloid hypothesis for new treatment strategies have set their sights on the idea of boosting the enzymatic destruction of the Aβ peptide. A flurry of recent papers and presentations at the 33rd Annual Meetin
