Entire Genome Yields to a Chip

RESEARCH NEWS 1997-11-24 Research News Researchers at California-based Affymetrix have analyzed the activity of every gene in the yeast genome in a single experiment using a new "DNA chip." This remarkable technological feat hints of a future, following completion of ...

Two New Genetic Risk Factors for Late-Onset Alzheimer’s Disease

RESEARCH NEWS 1997-10-16 Research News Scientists working in Oxford University and Duke University Medical Center this week reported the discovery of two new genetic risk factors for late-onset Alzheimer’s disease. Nearly 90 percent of all Alzheimer's cases are late-onset, ...

TGF-β1 Linked to Plaque Formation

RESEARCH NEWS 1997-10-09 Research News A history of brain injury raises a person’s risk of Alzheimer’s disease, and many researchers now suspect that the brain’s inflammatory responses to injury may magnify the neurodegenerative process. Now researchers have identified a ...

Antibodies Find a New Variety of Alzheimer's Plaque

RESEARCH NEWS 1997-06-27 Research News Researchers in Dr. John Q. Trojanowski's lab at the University of Pennsylvania have discovered a new type of lesion in the brains of Alzheimer's patients. These new lesions appear only in brains with amyloid plaques, including ...

MEDLINE Now Free to the Public

COMMUNITY NEWS 1997-06-26 Community News The National Library of Medicine's MEDLINE database is now accessible free to the general public through PubMed and Internet Grateful Med. Hot links to IGM and PubMed are available on the NLM home page. PubMed is an experimental search ...

Possible New Succeptability Genes for Alzheimer's Disease

RESEARCH NEWS 1997-04-29 Research News Put these two facts together: brain energy metabolism is abnormally low in Alzheimer's patients, and if your mother had Alzheimer's you are more likely to develop it than if your father had Alzheimer's. You might then ...

Vitamin E, Antioxidants and Alzheimer's Disease

RESEARCH NEWS 1997-04-24 Research News Results released today of a study published in the New England Journal of Medicine indicated that large doses of vitamin E may delay the time at which late-stage Alzheimer's patients must be institutionalized because of the loss of ...

Clues from the Colombian Countryside

RESEARCH NEWS 1997-03-12 Research News An enormous extended family living in a rural community in Colombia could provide new insights into environmental and genetic factors contributing to Alzheimer’s disease. All family members who were diagnosed with the disease carried an ...

Ibuprofen Linked to Reduced Alzheimer's Risk

RESEARCH NEWS 1997-03-10 Research News Ibuprofen and related drugs may reduce a person’s risk of getting Alzheimer’s disease by 30 to 60 percent, according to a new study by researchers at Johns Hopkins University and the National Institute on Aging. But the authors strongly ...

New Guidelines Proposed for Alzheimer's Disease Postmortem Diagnosis

COMMUNITY NEWS 1997-02-21 Community News An international group of researchers* have agreed upon recommendations to revise the criteria for postmortem diagnosis of Alzheimer’s disease (AD). The meeting, convened in November 13-14, 1996, at the National Institutes of Health in ...

ApoE4 Gene May Be Risk Factor in Only a Subset of Cases

RESEARCH NEWS 1997-02-21 Research News A new study reports that the ApoE4 gene, previously reported to be over-represented among patients with late onset Alzheimer's disease, appears to be a risk factor only among patients who developed the disease before age 70. The study ...

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