PAPER Pascoal TA, Chamoun M, Lax E, Wey HY, Shin M, Ng KP, Kang MS, Mathotaarachchi S, Benedet AL, Therriault J, Lussier FZ, Schroeder FA, DuBois JM, Hightower BG, Gilbert TM, Zürcher NR, Wang C, Hopewell R, Chakravarty M, Savard M, Thomas E, Mohaddes S, Farzin S, Salaciak A, Tullo S, Cuello AC, Soucy JP, Massarweh G, Hwang H, Kobayashi E, Hyman BT, Dickerson BC, Guiot MC, Szyf M, Gauthier S, Hooker JM, Rosa-Neto P
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PAPER Hausrat TJ, Janiesch PC, Breiden P, Lutz D, Hoffmeister-Ullerich S, Hermans-Borgmeyer I, Failla AV, Kneussel M
Disruption of tubulin-alpha4a polyglutamylation prevents aggregation of hyper-phosphorylated tau and microglia activation in mice.
Nat Commun. 2022 Jul 20;13(1):4192. PubMed: 35858909PAPER Tao Y, Sun Y, Lv S, Xia W, Zhao K, Xu Q, Zhao Q, He L, Le W, Wang Y, Liu C, Li D
Heparin induces α-synuclein to form new fibril polymorphs with attenuated neuropathology.
Nat Commun. 2022 Jul 22;13(1):4226. PubMed: 35869048PAPER Wingo TS, Liu Y, Gerasimov ES, Vattathil SM, Wynne ME, Liu J, Lori A, Faundez V, Bennett DA, Seyfried NT, Levey AI, Wingo AP
Shared mechanisms across the major psychiatric and neurodegenerative diseases.
Nat Commun. 2022 Jul 26;13(1):4314. PubMed: 35882878PAPER Lee A, Kondapalli C, Virga DM, Lewis TL Jr, Koo SY, Ashok A, Mairet-Coello G, Herzig S, Foretz M, Viollet B, Shaw R, Sproul A, Polleux F
Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy.
Nat Commun. 2022 Aug 1;13(1):4444. PubMed: 35915085PAPER Poulakis K, Pereira JB, Muehlboeck JS, Wahlund LO, Smedby Ö, Volpe G, Masters CL, Ames D, Niimi Y, Iwatsubo T, Ferreira D, Westman E, Japanese Alzheimer’s Disease Neuroimaging Initiative, Australian Imaging, Biomarkers and Lifestyle study
Multi-cohort and longitudinal Bayesian clustering study of stage and subtype in Alzheimer's disease.
Nat Commun. 2022 Aug 5;13(1):4566. PubMed: 35931678PAPER Gracia P, Polanco D, Tarancón-Díez J, Serra I, Bracci M, Oroz J, Laurents DV, García I, Cremades N
Molecular mechanism for the synchronized electrostatic coacervation and co-aggregation of alpha-synuclein and tau.
Nat Commun. 2022 Aug 6;13(1):4586. PubMed: 35933508PAPER Ayala Mariscal SM, Pigazzini ML, Richter Y, Özel M, Grothaus IL, Protze J, Ziege K, Kulke M, ElBediwi M, Vermaas JV, Colombi Ciacchi L, Köppen S, Liu F, Kirstein J
Identification of a HTT-specific binding motif in DNAJB1 essential for suppression and disaggregation of HTT.
Nat Commun. 2022 Aug 10;13(1):4692. PubMed: 35948542PAPER Korologou-Linden R, Bhatta L, Brumpton BM, Howe LD, Millard LA, Kolaric K, Ben-Shlomo Y, Williams DM, Smith GD, Anderson EL, Stergiakouli E, Davies NM
The causes and consequences of Alzheimer's disease: phenome-wide evidence from Mendelian randomization.
Nat Commun. 2022 Aug 11;13(1):4726. PubMed: 35953482PAPER C Silva T, Young JI, Zhang L, Gomez L, Schmidt MA, Varma A, Chen XS, Martin ER, Wang L
Cross-tissue analysis of blood and brain epigenome-wide association studies in Alzheimer's disease.
Nat Commun. 2022 Aug 18;13(1):4852. PubMed: 35982059PAPER Frontzkowski L, Ewers M, Brendel M, Biel D, Ossenkoppele R, Hager P, Steward A, Dewenter A, Römer S, Rubinski A, Buerger K, Janowitz D, Binette AP, Smith R, Strandberg O, Carlgren NM, Dichgans M, Hansson O, Franzmeier N
Earlier Alzheimer's disease onset is associated with tau pathology in brain hub regions and facilitated tau spreading.
Nat Commun. 2022 Aug 20;13(1):4899. PubMed: 35987901PAPER Pihlstrøm L, Shireby G, Geut H, Henriksen SP, Rozemuller AJ, Tunold JA, Hannon E, Francis P, Thomas AJ, Love S, Mill J, van de Berg WD, Toft M
Epigenome-wide association study of human frontal cortex identifies differential methylation in Lewy body pathology.
Nat Commun. 2022 Aug 22;13(1):4932. PubMed: 35995800PAPER Tahir UA, Katz DH, Avila-Pachecho J, Bick AG, Pampana A, Robbins JM, Yu Z, Chen ZZ, Benson MD, Cruz DE, Ngo D, Deng S, Shi X, Zheng S, Eisman AS, Farrell L, Hall ME, Correa A, Tracy RP, Durda P, Taylor KD, Liu Y, Johnson WC, Guo X, Yao J, Chen YI, Manichaikul AW, Ruberg FL, Blaner WS, Jain D, NHLBI Trans-Omics for Precision Medicine 1 Consortium, Bouchard C, Sarzynski MA, Rich SS, Rotter JI, Wang TJ, Wilson JG, Clish CB, Natarajan P, Gerszten RE
Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals.
Nat Commun. 2022 Aug 22;13(1):4923. PubMed: 35995766PAPER Xie YX, Naseri NN, Fels J, Kharel P, Na Y, Lane D, Burré J, Sharma M
Lysosomal exocytosis releases pathogenic α-synuclein species from neurons in synucleinopathy models.
Nat Commun. 2022 Aug 22;13(1):4918. PubMed: 35995799PAPER Ulamec SM, Maya-Martinez R, Byrd EJ, Dewison KM, Xu Y, Willis LF, Sobott F, Heath GR, van Oosten Hawle P, Buchman VL, Radford SE, Brockwell DJ
Single residue modulators of amyloid formation in the N-terminal P1-region of α-synuclein.
Nat Commun. 2022 Aug 25;13(1):4986. PubMed: 36008493Current Filters
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