PAPER Chen X, Liu X, Koundal S, Elkin R, Zhu X, Monte B, Xu F, Dai F, Pedram M, Lee H, Kipnis J, Tannenbaum A, Van Nostrand WE, Benveniste H
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PAPER Shulman M, Kong J, O'Gorman J, Ratti E, Rajagovindan R, Viollet L, Huang E, Sharma S, Racine AM, Czerkowicz J, Graham D, Li Y, Hering H, Haeberlein SB
TANGO: a placebo-controlled randomized phase 2 study of efficacy and safety of the anti-tau monoclonal antibody gosuranemab in early Alzheimer's disease.
Nat Aging. 2023 Dec;3(12):1591-1601. Epub 2023 Nov 27 PubMed: 38012285PAPER Stern AM, Sperling RA
Tangles, not TANGO: targeting tau aggregates.
Nat Aging. 2023 Dec;3(12):1472-1473. PubMed: 38012286PAPER
Protein levels in cerebrospinal fluid indicate different subtypes in Alzheimer's disease.
Nat Aging. 2024 Jan;4(1):12-13. PubMed: 38225434PAPER Oleson BJ, Bhattrai J, Zalubas SL, Kravchenko TR, Ji Y, Jiang EL, Lu CC, Madden CR, Coffman JG, Bazopoulou D, Jones JW, Jakob U
Early life changes in histone landscape protect against age-associated amyloid toxicities through HSF-1-dependent regulation of lipid metabolism.
Nat Aging. 2024 Jan;4(1):48-61. Epub 2023 Dec 6 PubMed: 38057386PAPER Tijms BM, Vromen EM, Mjaavatten O, Holstege H, Reus LM, van der Lee S, Wesenhagen KE, Lorenzini L, Vermunt L, Venkatraghavan V, Tesi N, Tomassen J, den Braber A, Goossens J, Vanmechelen E, Barkhof F, Pijnenburg YA, van der Flier WM, Teunissen CE, Berven FS, Visser PJ
Cerebrospinal fluid proteomics in patients with Alzheimer's disease reveals five molecular subtypes with distinct genetic risk profiles.
Nat Aging. 2024 Jan;4(1):33-47. Epub 2024 Jan 9 PubMed: 38195725PAPER
Blood protein markers predict 15-year risk of dementia.
Nat Aging. 2024 Feb;4(2):173-174. PubMed: 38347191PAPER Guo Y, You J, Zhang Y, Liu WS, Huang YY, Zhang YR, Zhang W, Dong Q, Feng JF, Cheng W, Yu JT
Plasma proteomic profiles predict future dementia in healthy adults.
Nat Aging. 2024 Feb;4(2):247-260. Epub 2024 Feb 12 PubMed: 38347190PAPER Li X, Li Y, Jin Y, Zhang Y, Wu J, Xu Z, Huang Y, Cai L, Gao S, Liu T, Zeng F, Wang Y, Wang W, Yuan TF, Tian H, Shu Y, Guo F, Lu W, Mao Y, Mei X, Rao Y, Peng B
Publisher Correction: Transcriptional and epigenetic decoding of the microglial aging process.
Nat Aging. 2024 Feb;4(2):276. PubMed: 38200274PAPER de Luzy IR, Lee MK, Mobley WC, Studer L
Lessons from inducible pluripotent stem cell models on neuronal senescence in aging and neurodegeneration.
Nat Aging. 2024 Mar;4(3):309-318. PubMed: 38429379PAPER Tang AS, Rankin KP, Cerono G, Miramontes S, Mills H, Roger J, Zeng B, Nelson C, Soman K, Woldemariam S, Li Y, Lee A, Bove R, Glymour M, Aghaeepour N, Oskotsky TT, Miller Z, Allen IE, Sanders SJ, Baranzini S, Sirota M
Leveraging electronic health records and knowledge networks for Alzheimer's disease prediction and sex-specific biological insights.
Nat Aging. 2024 Mar;4(3):379-395. Epub 2024 Feb 21 PubMed: 38383858PAPER Pan L, Li C, Meng L, Zhang G, Zou L, Tian Y, Chen S, Sun Y, Su D, Zhang X, Xiong M, Xiao T, Xia D, Hong Z, Zhang Z
GDF1 ameliorates cognitive impairment induced by hearing loss.
Nat Aging. 2024 Mar 15; PubMed: 38491289PAPER Zhao HB, Yang Y
Hearing loss promotes Alzheimer's disease.
Nat Aging. 2024 Mar 15; PubMed: 38491290PAPER Salvadó G, Horie K, Barthélemy NR, Vogel JW, Pichet Binette A, Chen CD, Aschenbrenner AJ, Gordon BA, Benzinger TL, Holtzman DM, Morris JC, Palmqvist S, Stomrud E, Janelidze S, Ossenkoppele R, Schindler SE, Bateman RJ, Hansson O
Disease staging of Alzheimer's disease using a CSF-based biomarker model.
Nat Aging. 2024 Mar 21; PubMed: 38514824PAPER Dvir-Szternfeld R, Castellani G, Arad M, Cahalon L, Phoebeluc Colaiuta S, Keren-Shaul H, Croese T, Burgaletto C, Baruch K, Ulland T, Colonna M, Weiner A, Amit I, Schwartz M
Alzheimer’s disease modification mediated by bone marrow-derived macrophages via a TREM2-independent pathway in mouse model of amyloidosis.
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