PAPER Zhan C, Chen Y, Tang Y, Wei G
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PAPER Bera S, Gayen N, Mohid SA, Bhattacharyya D, Krishnamoorthy J, Sarkar D, Choi J, Sahoo N, Mandal AK, Lee D, Bhunia A
Comparison of Synthetic Neuronal Model Membrane Mimics in Amyloid Aggregation at Atomic Resolution.
ACS Chem Neurosci. 2020 Jul 1;11(13):1965-1977. Epub 2020 Jun 19 PubMed: 32492332PAPER Krahn AI, Wells C, Drewry DH, Beitel LK, Durcan TM, Axtman AD
Defining the Neural Kinome: Strategies and Opportunities for Small Molecule Drug Discovery to Target Neurodegenerative Diseases.
ACS Chem Neurosci. 2020 Jul 1;11(13):1871-1886. Epub 2020 Jun 11 PubMed: 32464049PAPER Wesén E, Lundmark R, Esbjörner EK
Role of Membrane Tension Sensitive Endocytosis and Rho GTPases in the Uptake of the Alzheimer's Disease Peptide Aβ(1-42).
ACS Chem Neurosci. 2020 Jul 1;11(13):1925-1936. Epub 2020 Jun 22 PubMed: 32497421PAPER Gabr MT, Peccati F
Dual Targeting of Monomeric Tau and α-Synuclein Aggregation: A New Multitarget Therapeutic Strategy for Neurodegeneration.
ACS Chem Neurosci. 2020 Jul 15;11(14):2051-2057. Epub 2020 Jun 29 PubMed: 32579329PAPER Hu ZW, Au DF, Cruceta L, Vugmeyster L, Qiang W
N-Terminal Modified Aβ Variants Enable Modulations to the Structures and Cytotoxicity Levels of Wild-Type Aβ Fibrils through Cross-Seeding.
ACS Chem Neurosci. 2020 Jul 15;11(14):2058-2065. Epub 2020 Jul 6 PubMed: 32603584PAPER Townsend DJ, Mala B, Hughes E, Hussain R, Siligardi G, Fullwood NJ, Middleton DA
Circular Dichroism Spectroscopy Identifies the β-Adrenoceptor Agonist Salbutamol As a Direct Inhibitor of Tau Filament Formation in Vitro.
ACS Chem Neurosci. 2020 Jul 15;11(14):2104-2116. Epub 2020 Jul 6 PubMed: 32520518PAPER Baker JD, Uhrich RL, Strovas TJ, Saxton AD, Kraemer BC
Targeting Pathological Tau by Small Molecule Inhibition of the Poly(A):MSUT2 RNA-Protein Interaction.
ACS Chem Neurosci. 2020 Aug 5;11(15):2277-2285. Epub 2020 Jul 9 PubMed: 32589834PAPER Kreutzer AG, Samdin TD, Guaglianone G, Spencer RK, Nowick JS
X-ray Crystallography Reveals Parallel and Antiparallel β-Sheet Dimers of a β-Hairpin Derived from Aβ16-36 that Assemble to Form Different Tetramers.
ACS Chem Neurosci. 2020 Aug 5;11(15):2340-2347. Epub 2020 Jul 14 PubMed: 32584538PAPER Mason AJ, Hurst I, Malik R, Siddique I, Solomonov I, Sagi I, Klärner FG, Schrader T, Bitan G
Different Inhibitors of Aβ42-Induced Toxicity Have Distinct Metal-Ion Dependency.
ACS Chem Neurosci. 2020 Aug 5;11(15):2243-2255. Epub 2020 Jul 7 PubMed: 32559370PAPER Ryan P, Xu M, Jahan K, Davey AK, Bharatam PV, Anoopkumar-Dukie S, Kassiou M, Mellick GD, Rudrawar S
Novel Furan-2-yl-1H-pyrazoles Possess Inhibitory Activity against α-Synuclein Aggregation.
ACS Chem Neurosci. 2020 Aug 5;11(15):2303-2315. Epub 2020 Jul 8 PubMed: 32551538PAPER Sagnou M, Mavroidi B, Kaminari A, Boukos N, Pelecanou M
Novel Isatin Thiosemicarbazone Derivatives as Potent Inhibitors of β-Amyloid Peptide Aggregation and Toxicity.
ACS Chem Neurosci. 2020 Aug 5;11(15):2266-2276. Epub 2020 Jul 14 PubMed: 32598129PAPER Catto M, Pisani L, de la Mora E, Belviso BD, Mangiatordi GF, Pinto A, Palma A, Denora N, Caliandro R, Colletier JP, Silman I, Nicolotti O, Altomare CD
Chiral Separation, X-ray Structure, and Biological Evaluation of a Potent and Reversible Dual Binding Site AChE Inhibitor.
ACS Med Chem Lett. 2020 May 14;11(5):869-876. Epub 2020 Feb 7 PubMed: 32435398PAPER Franchini S, Linciano P, Puja G, Tait A, Borsari C, Denora N, Iacobazzi RM, Brasili L, Sorbi C
Novel Dithiolane-Based Ligands Combining Sigma and NMDA Receptor Interactions as Potential Neuroprotective Agents.
ACS Med Chem Lett. 2020 May 14;11(5):1028-1034. Epub 2020 Apr 3 PubMed: 32435421PAPER Cescon E, Bolcato G, Federico S, Bissaro M, Valentini A, Ferlin MG, Spalluto G, Sturlese M, Moro S