PAPER Alvariño R, Alonso E, Abbasov ME, Chaheine CM, Conner ML, Romo D, Alfonso A, Botana LM
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PAPER Chen Y, Xu J, Zhou X, Liu S, Zhang Y, Ma S, Fu AK, Ip NY, Chen Y
Changes of Protein Phosphorylation Are Associated with Synaptic Functions during the Early Stage of Alzheimer's Disease.
ACS Chem Neurosci. 2019 Sep 18;10(9):3986-3996. Epub 2019 Aug 29 PubMed: 31424205PAPER Chowdhury SR, Lu HP
Spontaneous Rupture and Entanglement of Human Neuronal Tau Protein Induced by Piconewton Compressive Force.
ACS Chem Neurosci. 2019 Sep 18;10(9):4061-4067. Epub 2019 Sep 6 PubMed: 31423763PAPER Dupré E, Danis C, Arrial A, Hanoulle X, Homa M, Cantrelle FX, Merzougui H, Colin M, Rain JC, Buée L, Landrieu I
Single Domain Antibody Fragments as New Tools for the Detection of Neuronal Tau Protein in Cells and in Mice Studies.
ACS Chem Neurosci. 2019 Sep 18;10(9):3997-4006. Epub 2019 Aug 19 PubMed: 31380615PAPER Krishna KV, Wadhwa G, Alexander A, Kanojia N, Saha RN, Kukreti R, Singhvi G, Dubey SK
Design and Biological Evaluation of Lipoprotein-Based Donepezil Nanocarrier for Enhanced Brain Uptake through Oral Delivery.
ACS Chem Neurosci. 2019 Sep 18;10(9):4124-4135. Epub 2019 Aug 29 PubMed: 31418556PAPER Laos V, Do TD, Bishop D, Jin Y, Marsh NM, Quon B, Fetters M, Cantrell KL, Buratto SK, Bowers MT
Characterizing TDP-43307-319 Oligomeric Assembly: Mechanistic and Structural Implications Involved in the Etiology of Amyotrophic Lateral Sclerosis.
ACS Chem Neurosci. 2019 Sep 18;10(9):4112-4123. Epub 2019 Sep 3 PubMed: 31430111PAPER Liang Z, Zhang B, Xu M, Morisseau C, Hwang SH, Hammock BD, Li QX
1-Trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) Urea, a Selective and Potent Dual Inhibitor of Soluble Epoxide Hydrolase and p38 Kinase Intervenes in Alzheimer's Signaling in Human Nerve Cells.
ACS Chem Neurosci. 2019 Sep 18;10(9):4018-4030. Epub 2019 Aug 19 PubMed: 31378059PAPER Parekh P, Sharma N, Gadepalli A, Shahane A, Sharma M, Khairnar A
A Cleaning Crew: The Pursuit of Autophagy in Parkinson's Disease.
ACS Chem Neurosci. 2019 Sep 18;10(9):3914-3926. Epub 2019 Aug 20 PubMed: 31385687PAPER Rabal O, Sánchez-Arias JA, Cuadrado-Tejedor M, de Miguel I, Pérez-González M, García-Barroso C, Ugarte A, Estella-Hermoso de Mendoza A, Sáez E, Espelosin M, Ursua S, Tan H, Wu W, Xu M, Pineda-Lucena A, Garcia-Osta A, Oyarzabal J
Multitarget Approach for the Treatment of Alzheimer's Disease: Inhibition of Phosphodiesterase 9 (PDE9) and Histone Deacetylases (HDACs) Covering Diverse Selectivity Profiles.
ACS Chem Neurosci. 2019 Sep 18;10(9):4076-4101. Epub 2019 Sep 4 PubMed: 31441641PAPER Chen J, Wang J, Yin B, Pang L, Wang W, Zhu W
Molecular Mechanism of Binding Selectivity of Inhibitors toward BACE1 and BACE2 Revealed by Multiple Short Molecular Dynamics Simulations and Free-Energy Predictions.
ACS Chem Neurosci. 2019 Oct 16;10(10):4303-4318. Epub 2019 Oct 2 PubMed: 31545898PAPER Doens D, Valdés-Tresanco ME, Vasquez V, Carreira MB, De La Guardia Y, Stephens DE, Nguyen VD, Nguyen VT, Gu J, Hegde ML, Larionov OV, Valiente PA, Lleonart R, Fernández PL
Hexahydropyrrolo[2,3-b]indole Compounds as Potential Therapeutics for Alzheimer's Disease.
ACS Chem Neurosci. 2019 Oct 16;10(10):4250-4263. Epub 2019 Oct 7 PubMed: 31545596PAPER Paudel YN, Angelopoulou E, Jones NC, O'Brien TJ, Kwan P, Piperi C, Othman I, Shaikh MF
Tau Related Pathways as a Connecting Link between Epilepsy and Alzheimer's Disease.
ACS Chem Neurosci. 2019 Oct 16;10(10):4199-4212. Epub 2019 Sep 30 PubMed: 31532186PAPER Press-Sandler O, Miller Y
Distinct Primary Nucleation of Polymorphic Aβ Dimers Yields to Distinguished Fibrillation Pathways.
ACS Chem Neurosci. 2019 Oct 16;10(10):4407-4413. Epub 2019 Sep 26 PubMed: 31532176PAPER Sharma P, Tripathi A, Tripathi PN, Singh SS, Singh SP, Shrivastava SK
Novel Molecular Hybrids of N-Benzylpiperidine and 1,3,4-Oxadiazole as Multitargeted Therapeutics to Treat Alzheimer's Disease.
ACS Chem Neurosci. 2019 Oct 16;10(10):4361-4384. Epub 2019 Sep 19 PubMed: 31491074PAPER Arya S, Claud SL, Cantrell KL, Bowers MT