PAPER Laos V, Do TD, Bishop D, Jin Y, Marsh NM, Quon B, Fetters M, Cantrell KL, Buratto SK, Bowers MT
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PAPER Liang Z, Zhang B, Xu M, Morisseau C, Hwang SH, Hammock BD, Li QX
1-Trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) Urea, a Selective and Potent Dual Inhibitor of Soluble Epoxide Hydrolase and p38 Kinase Intervenes in Alzheimer's Signaling in Human Nerve Cells.
ACS Chem Neurosci. 2019 Sep 18;10(9):4018-4030. Epub 2019 Aug 19 PubMed: 31378059PAPER Parekh P, Sharma N, Gadepalli A, Shahane A, Sharma M, Khairnar A
A Cleaning Crew: The Pursuit of Autophagy in Parkinson's Disease.
ACS Chem Neurosci. 2019 Sep 18;10(9):3914-3926. Epub 2019 Aug 20 PubMed: 31385687PAPER Rabal O, Sánchez-Arias JA, Cuadrado-Tejedor M, de Miguel I, Pérez-González M, García-Barroso C, Ugarte A, Estella-Hermoso de Mendoza A, Sáez E, Espelosin M, Ursua S, Tan H, Wu W, Xu M, Pineda-Lucena A, Garcia-Osta A, Oyarzabal J
Multitarget Approach for the Treatment of Alzheimer's Disease: Inhibition of Phosphodiesterase 9 (PDE9) and Histone Deacetylases (HDACs) Covering Diverse Selectivity Profiles.
ACS Chem Neurosci. 2019 Sep 18;10(9):4076-4101. Epub 2019 Sep 4 PubMed: 31441641PAPER Zhou H, Yang Z, Tian X, Chen L, Lee S, Huynh T, Ge C, Zhou R
Lanosterol Disrupts the Aggregation of Amyloid-β Peptides.
ACS Chem Neurosci. 2019 Sep 18;10(9):4051-4060. Epub 2019 Aug 15 PubMed: 31369236PAPER Chen J, Wang J, Yin B, Pang L, Wang W, Zhu W
Molecular Mechanism of Binding Selectivity of Inhibitors toward BACE1 and BACE2 Revealed by Multiple Short Molecular Dynamics Simulations and Free-Energy Predictions.
ACS Chem Neurosci. 2019 Oct 16;10(10):4303-4318. Epub 2019 Oct 2 PubMed: 31545898PAPER Doens D, Valdés-Tresanco ME, Vasquez V, Carreira MB, De La Guardia Y, Stephens DE, Nguyen VD, Nguyen VT, Gu J, Hegde ML, Larionov OV, Valiente PA, Lleonart R, Fernández PL
Hexahydropyrrolo[2,3-b]indole Compounds as Potential Therapeutics for Alzheimer's Disease.
ACS Chem Neurosci. 2019 Oct 16;10(10):4250-4263. Epub 2019 Oct 7 PubMed: 31545596PAPER Paudel YN, Angelopoulou E, Jones NC, O'Brien TJ, Kwan P, Piperi C, Othman I, Shaikh MF
Tau Related Pathways as a Connecting Link between Epilepsy and Alzheimer's Disease.
ACS Chem Neurosci. 2019 Oct 16;10(10):4199-4212. Epub 2019 Sep 30 PubMed: 31532186PAPER Press-Sandler O, Miller Y
Distinct Primary Nucleation of Polymorphic Aβ Dimers Yields to Distinguished Fibrillation Pathways.
ACS Chem Neurosci. 2019 Oct 16;10(10):4407-4413. Epub 2019 Sep 26 PubMed: 31532176PAPER Sharma P, Tripathi A, Tripathi PN, Singh SS, Singh SP, Shrivastava SK
Novel Molecular Hybrids of N-Benzylpiperidine and 1,3,4-Oxadiazole as Multitargeted Therapeutics to Treat Alzheimer's Disease.
ACS Chem Neurosci. 2019 Oct 16;10(10):4361-4384. Epub 2019 Sep 19 PubMed: 31491074PAPER Arya S, Claud SL, Cantrell KL, Bowers MT
Catalytic Prion-Like Cross-Talk between a Key Alzheimer's Disease Tau-Fragment R3 and the Type 2 Diabetes Peptide IAPP.
ACS Chem Neurosci. 2019 Nov 20;10(11):4757-4765. Epub 2019 Nov 5 PubMed: 31642657PAPER Asadbegi M, Shamloo A
Identification of a Novel Multifunctional Ligand for Simultaneous Inhibition of Amyloid-Beta (Aβ42) and Chelation of Zinc Metal Ion.
ACS Chem Neurosci. 2019 Nov 20;10(11):4619-4632. Epub 2019 Oct 10 PubMed: 31566950PAPER Devitt G, Rice W, Crisford A, Nandhakumar I, Mudher A, Mahajan S
Conformational Evolution of Molecular Signatures during Amyloidogenic Protein Aggregation.
ACS Chem Neurosci. 2019 Nov 20;10(11):4593-4611. Epub 2019 Oct 29 PubMed: 31661242PAPER Hao S, Li X, Han A, Yang Y, Fang G, Liu J, Wang S
CLVFFA-Functionalized Gold Nanoclusters Inhibit Aβ40 Fibrillation, Fibrils' Prolongation, and Mature Fibrils' Disaggregation.
ACS Chem Neurosci. 2019 Nov 20;10(11):4633-4642. Epub 2019 Nov 4 PubMed: 31637909PAPER Horvath I, Blockhuys S, Šulskis D, Holgersson S, Kumar R, Burmann BM, Wittung-Stafshede P