PAPER Lindstedt PR, Aprile FA, Matos MJ, Perni M, Bertoldo JB, Bernardim B, Peter Q, Jiménez-Osés G, Knowles TP, Dobson CM, Corzana F, Vendruscolo M, Bernardes GJ
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PAPER Bhattarai A, Devkota S, Bhattarai S, Wolfe MS, Miao Y
Mechanisms of γ-Secretase Activation and Substrate Processing.
ACS Cent Sci. 2020 Jun 24;6(6):969-983. Epub 2020 Jun 4 PubMed: 32607444PAPER Pan B, Rhoades E, Petersson EJ
Chemoenzymatic Semisynthesis of Phosphorylated α-Synuclein Enables Identification of a Bidirectional Effect on Fibril Formation.
ACS Chem Biol. 2020 Mar 20;15(3):640-645. Epub 2020 Feb 17 PubMed: 32065743PAPER Ramirez DH, Aonbangkhen C, Wu HY, Naftaly JA, Tang S, O'Meara TR, Woo CM
Engineering a Proximity-Directed O-GlcNAc Transferase for Selective Protein O-GlcNAcylation in Cells.
ACS Chem Biol. 2020 Apr 17;15(4):1059-1066. Epub 2020 Mar 2 PubMed: 32119511PAPER Sachsenhauser V, Deng X, Kim HH, Jankovic M, Bardwell JC
Yeast Tripartite Biosensors Sensitive to Protein Stability and Aggregation Propensity.
ACS Chem Biol. 2020 Apr 17;15(4):1078-1088. Epub 2020 Mar 10 PubMed: 32105441PAPER Bilousova T, Simmons BJ, Knapp RR, Elias CJ, Campagna J, Melnik M, Chandra S, Focht S, Zhu C, Vadivel K, Jagodzinska B, Cohn W, Spilman P, Gylys KH, Garg NK, John V
Dual Neutral Sphingomyelinase-2/Acetylcholinesterase Inhibitors for the Treatment of Alzheimer's Disease.
ACS Chem Biol. 2020 Jun 19;15(6):1671-1684. Epub 2020 May 14 PubMed: 32352753PAPER Viet MH, Nguyen PH, Ngo ST, Li MS, Derreumaux P
Effect of the Tottori familial disease mutation (D7N) on the monomers and dimers of Aβ40 and Aβ42.
ACS Chem Neurosci. 2013 Nov 20;4(11):1446-57. Epub 2013 Sep 16 PubMed: 24041307PAPER Matthes D, Gapsys V, Griesinger C, de Groot BL
Resolving the Atomistic Modes of Anle138b Inhibitory Action on Peptide Oligomer Formation.
ACS Chem Neurosci. 2017 Dec 20;8(12):2791-2808. Epub 2017 Sep 28 PubMed: 28906103PAPER Aftabizadeh M, Tatarek-Nossol M, Andreetto E, El Bounkari O, Kipp M, Beyer C, Latz E, Bernhagen J, Kapurniotu A
Blocking Inflammasome Activation Caused by β-Amyloid Peptide (Aβ) and Islet Amyloid Polypeptide (IAPP) through an IAPP Mimic.
ACS Chem Neurosci. 2019 Aug 21;10(8):3703-3717. Epub 2019 Jul 25 PubMed: 31295403PAPER Angira D, Chikhale R, Mehta K, Bryce RA, Thiruvenkatam V
Tracing the GSAP-APP C-99 Interaction Site in the β-Amyloid Pathway Leading to Alzheimer's Disease.
ACS Chem Neurosci. 2019 Aug 21;10(8):3868-3879. Epub 2019 Jul 26 PubMed: 31299145PAPER Capucciati A, Galliano M, Bubacco L, Zecca L, Casella L, Monzani E, Nicolis S
Neuronal Proteins as Targets of 3-Hydroxykynurenine: Implications in Neurodegenerative Diseases.
ACS Chem Neurosci. 2019 Aug 21;10(8):3731-3739. Epub 2019 Jul 26 PubMed: 31298828PAPER Choi H, Lee W, Lee G, Yoon DS, Na S
The Formation Mechanism of Segmented Ring-Shaped Aβ Oligomers and Protofibrils.
ACS Chem Neurosci. 2019 Aug 21;10(8):3830-3838. Epub 2019 Jul 30 PubMed: 31313912PAPER Drake LR, Pham JM, Desmond TJ, Mossine AV, Lee SJ, Kilbourn MR, Koeppe RA, Brooks AF, Scott PJ
Identification of AV-1451 as a Weak, Nonselective Inhibitor of Monoamine Oxidase.
ACS Chem Neurosci. 2019 Aug 21;10(8):3839-3846. Epub 2019 Aug 5 PubMed: 31339297PAPER Foley AR, Finn TS, Kung T, Hatami A, Lee HW, Jia M, Rolandi M, Raskatov JA
Trapping and Characterization of Nontoxic Aβ42 Aggregation Intermediates.
ACS Chem Neurosci. 2019 Aug 21;10(8):3880-3887. Epub 2019 Aug 1 PubMed: 31319029PAPER Ghio S, Camilleri A, Caruana M, Ruf VC, Schmidt F, Leonov A, Ryazanov S, Griesinger C, Cauchi RJ, Kamp F, Giese A, Vassallo N