PAPER Klein HU, McCabe C, Gjoneska E, Sullivan SE, Kaskow BJ, Tang A, Smith RV, Xu J, Pfenning AR, Bernstein BE, Meissner A, Schneider JA, Mostafavi S, Tsai LH, Young-Pearse TL, Bennett DA, De Jager PL
SEARCH RESULTS
255723 RESULTS
PAPER Guerreiro R, Sassi C, Gibbs J, Edsall C, Hernandez D, Brown K, Lupton M, Parkinnen L, Ansorge O, Hodges A, Ryten M, Tienari P, Van Deerlin V, Trojanowski J, Morgan K, Powell J, Singleton A, Hardy J, Bras J
A comprehensive assessment of benign genetic variability for neurodegenerative disorders
bioRχiv. February 23, 2018PAPER Srivastava PK, van Eyll J, Godard P, Mazzuferi M, Danis B, Vandenplas C, Foerch P, Leclercq K, Mairet-Coello G, Vanclef F, Shkura K, Laaniste L, Delahaye-Duriez A, Kaminski RM, Petretto E, Johnson MR
A Systems-Level Framework For Drug Discovery Identifies Csf1R As A Novel Anti-Epileptic Drug Target
bioXriv, May 22, 2017PAPER Goodwin LO, Splinter E, Davis TL, Urban R, He H, Braun RE, Chesler EJ, Kumar V, van Min M, Ndukum J, Philip VM, Reinholdt LG, Svenson K, White JK, Sasner M, Lutz C, Murray SA
Large-scale discovery of mouse transgenic integration sites reveals frequent structural variation and insertional mutagenesis
bioRχiv preprint first posted online Dec. 18, 2017PAPER Brownjohn PW, Smith J, Solanki R, Lohmann E, Houlden H, Hardy J, Dietmann S, Livesey FJ
Functional Studies of Missense TREM2 Mutations in Human Stem Cell-Derived Microglia.
Stem Cell Reports, March 29, 2018.PAPER Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Alzheimer's Disease Genetics Consortium (ADGC), European Alzheimer's Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE), Genetic and Environmental Risk in Alzheimer's Disease Consortium (GERAD/PERADES), Schmidt H, Hakonarson H, Munger R, Schmidt R, Farrer LA, Van Broeckhoven C, O'Donovan MC, Destefano AL, Jones L, Haines JL, Deleuze JF, Owen MJ, Gudnason V, Mayeux RP, Escott-Price V, Psaty BM, Ruiz A, Ramirez A, Wang LS, van Duijn CM, Holmans PA, Seshadri S, Williams J, Amouyel P, Schellenberg GD, Lambert JC, Pericak-Vance MA
Meta-analysis of genetic association with diagnosed Alzheimer's disease identifies novel risk loci and implicates Abeta, Tau, immunity and lipid processing
bioRχiv. 2018 Apr 5PAPER Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Alzheimer's Disease Genetics Consortium (ADGC), European Alzheimer's Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE), Genetic and Environmental Risk in Alzheimer's Disease Consortium (GERAD/PERADES), Schmidt H, Hakonarson H, Munger R, Schmidt, Farrer LA, Broeckhoven CV, O'Donovan MC, Destefano AL, Jones L, Haines JL, Deleuze JF, Owen MJ, Gudnason V, Mayeux RP, Escott-Price V, Psaty BM, Ruiz A, Ramirez A, Wang LS, van Duijn CM, Holmans PA, Seshadri S, Williams J, Amouyel P, Schellenberg GD, Lambert JC, Pericak-Vance MA
Meta-analysis of genetic association with diagnosed Alzheimer's disease identifies novel risk loci and implicates Abeta, Tau, immunity and lipid processing
bioRxiv. April 5, 2018.PAPER Gordon BA, McCullough A, Mishra S, Blazey TM, Su Y, Christensen J, Dincer A, Jackson K, Hornbeck RC, Morris JC, Ances BM, Benzinger TL
Cross-sectional and longitudinal atrophy is preferentially associated with tau rather than amyloid β; positron emission tomography pathology
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 2018.PAPER Ingelsson M et al
Lack of correlation between biochemical and neuropathological amyloid measures in the Alzheimer brain
Ana Aslan International Academy of Aging 2003; pp 191-8.PAPER Illán-Gala I, Pegueroles J, Montal V, Vilaplana E, Carmona-Iragui M, Alcolea D, Dickerson BC, Sánchez-Valle R, de Leon MJ, Blesa R, Lleó A, Fortea J
Challenges associated with biomarker-based classification systems for Alzheimer's disease
Alzheimer's & Dementia, April 19, 2018PAPER Betthauser TJ, Cody KA, Zammit MD, Murali D, Converse AK, Barnhart TE, Stone CK, Rowley HA, Johnson SC, Christian BT
In vivo characterization and quantification of neurofibrillary tau PET radioligand [18F]MK-6240 in humans from Alzheimer's disease dementia to young controls
bioRχiv 290064; Apri 25, 2018PAPER Sun J, Carlson-Stevermer J, Das U, Shen M, Delenclos M, Snead A, Wang L, Loi J, Petersen A, Stockton M, Bhattacharyya A, Jones M, Sproul A, McLean P, Zhao X, Saha K, Roy S
A CRISPR/Cas9 based strategy to manipulate the Alzheimer's amyloid pathway
bioRχiv 310193; Apri 28, 2018PAPER Wong DF, Comley RA, Kuwabara H, Rosenberg P, Resnick SM, Ostrowitzki S, Vozzi C, Boess F, Oh E, Lyketsos CG, Horner M, Gobbi L, Klein G, George N, Gapasin L, Kitzmiller K, Roberts J, Sevigny J, Nandi A, Brasic J, Mishra C, Thambisetty M, Mogekar A, Mathur A, Albert M, Dannals RF, Borroni E
First in-human PET study of 3 novel tau radiopharmaceuticals: [11C]RO6924963, [11C]RO6931643, and [18F]RO6958948
J Nucl Med jnumed.118.209916 published ahead of print May 4, 2018PAPER Barnes DE, Byers AL, Gardner RC, Seal KH, Boscardin J, Yaffe K
Association of mild traumatic brain injury with and without loss of consciousness with dementia in U.S. military veterans.
JAMA Neurol. 2018 May 7.PAPER Kenney K, Diaz-Arrastia R