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Bcl-2 (124)

ANTIBODY monoclonal 124 manufacturer Cat #PDM 016 immunogen = synthetic peptide corresp. to aa. 51-54 of bcl-2 liquid, supernatant, prediluted Bcl-2 (25 kDa) protein; stains neoplastic and lymphoblastic lymphomas and anaplasticlarge cell lymphoma. IgG<sub>1 ...

Bcl-6

ANTIBODY polyclonal manufacturer Cat #PDR 012 immunogen = synthetic peptide corr. to aa. 687-706, mapping at the C-terminus of human bcl-6 liquid, prediluted detects 79 kDa bcl-6 . not  IH(P) Cell Death Biotrend Rabbit Immunohistochemistry Human Mouse Rat Bcl-6 ...

Bcl-2 (83-8B)

ANTIBODY monoclonal 83-8B manufacturer Cat# AAM-072E immunogen = recombinant rat Bcl-2β protein mouse IgG, PBS,glycerol, protein-A purified detects ~26 kDa Bcl-2 IgG<sub>1</sub> Cell Death Biotrend Mouse Western Blot Human Mouse Rat Bcl-2 http:/ ...

Bcl-2 (124)

ANTIBODY monoclonal 124 manufacturer cat# F7053 immunogen = synthetic peptide corresp. to aa. 41-54 of human bcl-2 oncoprotein liquid, BSA, azide, purified, conj. FITC Bcl-2, 25 kDa IgG<sub>1</sub>κ Cell Death Dako Mouse Flow Cytometry Immunoblotting ...

Bcl-2 (124)

ANTIBODY monoclonal 124 manufacturer cat# M0887 immunogen = synthetic peptide corr. to aa. 41-54 of bcl-2 protein liquid, supernatant, Tris/HCl, azide specific to Bcl-2, 25 kDa IgG<sub>1</sub>κ Cell Death Dako Mouse Immunohistochemistry Human Bcl-2 ...

Tau phos Ser721

ANTIBODY polyclonal manufacturer Cat#<br />sc-16944 immunogen = short aa seq. containing phosphorylated Ser721 of human Tau liquid, PBS, gelatin, azide, affinity purified; blocking peptide sc-16944P Ser721 phosphorylated tau IgG Tau Santa Cruz Goat ...

APPSwe (line C3-3)

RESEARCH MODELS Summary These transgenic mice express a chimeric mouse/human APP carrying the Swedish mutation under the control of the mouse prion protein promoter. This line, C3-3, was generated in parallel with line E1-2, which also expresses APP carrying the Swedish ...

PSEN1 Knock-out

RESEARCH MODELS Summary These mice are deficient in PSEN1. This model is perinatal lethal in homozygouse animals which die shortly after birth, presumably from breathing difficulties due to ribcage deformity (Shen et al., 1997). Gross skeletal malformations and central ...

PS1(M146L)

RESEARCH MODELS Summary The first report of this transgenic line described two lines of mice that overexpress human PSEN1 with the M146L mutation, line 5.1 and line 6.2 (Duff et al., 1996). Line 5.1 has been more extensively characterized, especially in relation to the ...

APP(V717I)

RESEARCH MODELS Modification Details Transgene containing human APP (isoform 695) with the London mutation driven by the Thy1 promoter. Neuropathology Plaques start in the subiculum at ten months, spreading to the frontal cortex as dense and diffuse aggregates. Frequent ...

APP(V717I) x PS1(A246E)

RESEARCH MODELS Summary These are bigenic mice that overexpress both mutant APP (V717I mutation) and mutant PSEN1 (A246E mutation). They were first generated and described by the laboratory of Fred Van Leuven (Dewachter et al., 2000). The transgenes are coexpressed in ...

Senescence Accelerated Mouse (SAMP8)

RESEARCH MODELS Summary The Senescence Accelerated Mouse-Prone 8 (SAMP8) is a naturally occuring mouse line that displays a phenotype of accelerated aging. While maintaining an inbred AKR/J line in the early 1970's, researchers at Kyoto University became aware that ...

Tau P301L

RESEARCH MODELS Neuropathology Tau hyperphosphorylation and conformational changes in the brain parenchyma start around seven months. Tangle-like pathology is mainly observed in the brain stem and spinal cord, and to a lesser extent in the midbrain and cerebral cortex ...

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