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Presenilin Loss of Function—Plan B for AD?

WEBINAR 2007-03-09 These are comfortable times for the amyloid hypothesis, it would seem. Every week brings more good news about some anti-amyloid intervention having “cured” mice from their “Alzheimer’s.” On the human front, we are eagerly awaiting such therapeutics to ...

Leon Thal Symposium Webinar

WEBINAR 2008-11-04 On Monday, 27 October 2008, a live Webinar was held by Alzheimer’s research leaders on a national action plan to accelerate discoveries of treatments to prevent dementia. The plan will be presented to the 111th U.S. Congress in March 2009. Presentations ...

Betwixt and Intermixed—Dementia With Lewy Bodies

WEBINAR 2009-06-15 On 15 June 2009, we hosted a Webinar discussion with slide presentations by Ian McKeith at Newcastle University, UK, James Leverenz at University of Washington, Seattle, James Galvin, Washington University, St. Louis, Brit Mollenhauer of Paracelsus-Elena ...

Herpes Simplex and Alzheimer’s—Time to Think Again?

WEBINAR 2011-04-15 On Thursday, 24 February 2011, Ruth Itzhaki, University of Manchester, U.K.; Elisa Porcellini, University of Bologna, Italy; Luc Letenneur, INSERM, Bordeaux, France, and Richard Smeyne, St. Jude Children’s Research Hospital, Memphis, Tennessee, shared ...

Cell Death: Time to Push It Out of the Doldrums

WEBINAR 2004-09-10 We invite you to participate in this Forum Discussion with Yong Shen (Sun Health Research Institute). This discussion will not be hosted via our live discussion software. Instead, we will develop written exchanges between our participants and Yong Shen. ...

Reimagining Alzheimer's Disease—Time for Bright New Ideas?

WEBINAR 2011-05-03 Alois Alzheimer made a major breakthrough when he discovered senile plaques in the brains of dementia patients, and his work ultimately led to the discovery of amyloid-β and to the amyloid cascade hypothesis. But that cascade is only part of a much bigger ...

Calcium Signaling Deficit in the Origin of Alzheimer's Disease

WEBINAR 2001-09-07 Live discussion and panel of participants scheduled for 7 September 2001.      Summary: "Ca2+ deficit" hypothesis Summary: "Natural origin" hypothesis for plaques and tangles The live chat and panel of participants scheduled for 7 ...

β Amyloid Degradation: The Forgotten Half of Alzheimer's Disease

WEBINAR 2002-09-12 Malcolm Leissring and Wesley Farris led this live discussion on 12 September 2002. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Live discussion held 12 September 2002 with Wesley ...

The Cell Cycle and Alzheimer’s Disease—Let's Unite for Division!

WEBINAR 2002-08-07 Inez Vincent led this live discussion on 7 August 2002. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. See diagram from Inez Vincent Transcript: Live discussion held 20 May 2002 at 12 noon. ...

The AD8—Dementia Screen Ready for Prime Time?

WEBINAR 2010-12-02 Have you been waiting for a quick yet reliable test for early dementia? The AD8 might be your answer. The interview-based screening tool detects early cognitive impairment, has been validated against the clinical dementia rating scale and against ...

In Search of γ-Secretase

WEBINAR 1999-05-05 Peter Nelson, with Dennis Selkoe, John Hardy, and Alain Israel, led this live discussion on 5 May 1999. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Live discussion with Dennis Selkoe, ...

Nomenclature Discussion

WEBINAR 2001-08-15 George Perry and Mark A. Smith led this live discussion on 14 August 2001. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Live discussion held 14 August 2001, 5 p.m. EST Participants: ...

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