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Parsing Local and Distal Aβ Shows Links to Metabolism, Cognition

RESEARCH NEWS 2019-06-14 Research News For decades, researchers have wondered why Aβ deposits in the brain correlate poorly with local neural activity and cognition. Perhaps the correlation was not that weak, after all. A study in the June 4 Nature Communications suggests that it ...

Dead Microglia Pave the Way for Myelin Regeneration

RESEARCH NEWS 2019-06-12 Research News In brain disease, microglia can be villains or heroes. How to encourage the latter? In the June 10 Nature Neuroscience, researchers led by Veronique Miron at the University of Edinburgh tried by killing off the troublemakers. In a mouse ...

Two Proteins in Young Blood Give Synapses a SPARC

RESEARCH NEWS 2019-06-11 Research News Human neurons sprouted more synapses and fired off more action potentials when bathed in serum from young, but not old, mice, according to a study published June 3 in Proceedings of the National Academy of Sciences. Kathlyn Gan and Thomas ...

Study Strengthens Link between Hepatitis C Virus, Parkinson’s

RESEARCH NEWS 2019-06-13 Research News Epidemiology has tied infection with hepatitis C to an increased risk for Parkinson’s disease. But what happens when the infection is treated? By surveying medical records of nearly 200,000 patients, researchers led by Ying-Zu Huang and Rou ...

Sliced by ApoE Genotype, Whole Exome Data Yield New AD Variants

RESEARCH NEWS 2019-06-14 Research News Does the head honcho of genetic Alzheimer’s risk occlude contributions of smaller genes? In the June 10 JAMA Neurology, researchers led by Lindsay Farrer at Boston University exposed some hidden variants that have languished in the shadow of ...

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