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Blood-Brain Barrier Surprise: Proteins Flood into Young Brain

RESEARCH NEWS 2020-07-02 Research News The blood-brain barrier keeps most plasma proteins out of the brain, but becomes leaky with age and in Alzheimer’s. Or so scientists thought. In the July 1 Nature, researchers led by Tony Wyss-Coray at Stanford University turn this idea on ...

Women and Men Differ in Their Genetic Risk for Alzheimer’s Progression

RESEARCH NEWS 2020-07-02 Research News Researchers are beginning to assess how genetic variation influences sex differences in Alzheimer’s disease. True, women who have an ApoE4 allele are more likely to develop Alzheimer’s than are male carriers, but what about the many other ...

Does a Stimulating Childhood Stem Amyloid Plaques in Golden Years?

RESEARCH NEWS 2020-07-02 Research News A childhood rich with intellectual stimulation may help the brain resist the onslaught of Alzheimer’s disease decades later, according to a study published June 29 in JAMA Neurology. Researchers led by David Bennett at Rush University ...

RBFOX1 Gene Tied to Amyloidosis in Preclinical Alzheimer’s

RESEARCH NEWS 2020-06-30 Research News Massive genome-wide association studies for Alzheimer’s disease have primarily correlated genetic variants with clinical diagnosis, a rubric that is fraught with uncertainty. In a GWAS published June 22 in JAMA Neurology, researchers led by ...

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