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Cell-Specific Enhancer Atlas Centers AD Risk in Microglia. Again.

RESEARCH NEWS 2019-11-16 Research News Most GWAS hits lie in noncoding regions of the genome, making it hard to figure out what they do. To address this, researchers led by Christopher Glass at the University of California, San Diego, analyzed epigenetic data from purified ...

Dipeptide Repeat Proteins Don’t Directly Block Nuclear Transport

RESEARCH NEWS 2019-11-15 Research News Lots of evidence suggests dipeptide repeat proteins translated from hexanucleotide repeat expansions in C9ORF72 interfere with transport of proteins in and out of the cell’s nucleus. However, an October 31 paper in Scientific Reports ...

Already in Mid-30s, Poor Vascular Health Means Small Brain at 70

RESEARCH NEWS 2019-11-13 Research News Updated November 14, 2019 Thirty-somethings take heed. A new study suggests it’s time to take care of your vascular health. Using data from the longest continuously running birth cohort in the world, researchers led by Jonathan Schott of ...

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