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Paper Alert: VCAM1 Opens the Door to Brain Aging

RESEARCH NEWS 2019-05-18 Research News Mysterious factors in the blood are known to trigger aging in the brain. Though researchers have yet to discover the identities of all these aging agents, they have pegged a protein that lets them do their dirty work. On May 13 in Nature ...

BACE Inhibitors: Postmortem on One, Live Updates on Two

CONFERENCE COVERAGE 2019-05-17 Conference Coverage At the AD/PD 2019 conference held recently in Lisbon, the amyloid hypothesis was reeling from repeated gut punches in the clinic. Both antibodies and BACE inhibitors are facing relentless criticism from academic scientists and ...

Plasticity Hums With Protein Synthesis on Both Sides of Synapse

RESEARCH NEWS 2019-05-17 Research News Scientists know that synaptic plasticity requires local protein production from translation of mRNAs in postsynaptic dendrites. However, local synthesis had not been clearly demonstrated on the other, presynaptic side in mature axons. A new ...

Gamma Waves Synchronized by Light: Good for Synapses, Memory?

RESEARCH NEWS 2019-05-17 Research News If using flashing lights to treat Alzheimer’s disease sounds like science fiction, then brace yourself, because new data strengthen the case for this idea. Previously, Li-Huei Tsai and colleagues at MIT had reported that a treatment ...

WHO Weighs in With Guidelines for Preventing Dementia

COMMUNITY NEWS 2019-05-17 Community News Many researchers and advocacy groups tout the benefits of a healthy lifestyle for preventing cognitive decline and dementia. Now the World Health Organization has weighed in, releasing a set of guidelines for lowering risk. The guidelines ...

Keep Your Enthusiasm? Scientists Process Brutal Trial Data

CONFERENCE COVERAGE 2019-05-16 Conference Coverage “There is a lot of bad news, but it’s useful bad news.” This line by Randy Bateman of Washington University, St. Louis, captured the mood at the AD/PD conference held March 27 to 31 in Lisbon, Portugal. Whereas in years past scientists ...

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