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PAPER Tang JX, Eckenhoff MF
Anesthetic effects in Alzheimer transgenic mouse models.
Prog Neuropsychopharmacol Biol Psychiatry. 2012 Jun 13; PubMed: 22705294PAPER Matías-Guiu JA, García-Ramos R
Primary progressive aphasia: from syndrome to disease.
Neurologia. 2012 Jun 13; PubMed: 22703637Jonathan Brouillette on Research Brief: Assessing Aβ Oligomers Toxicity in Live Mice
COMMENT Many advantages can be attributed to this novel, flexible in-vivo approach: The nature of toxic Aβ intermediates can be more accurately controlled by injecting Aβ preparations that are characterized before and after chronic injection, as we did in our pap
Ralph Nixon on Evidence Piles Up for Lysosomal Dysfunction in Parkinson’s
COMMENT The lysosomal acidification defect linked to cytotoxicity of mutations in the P-type ATPase ATP13A2/PARK9 in Parkinson’s disease (PD) prompts comparison to the similar mechanism operating in AD due to mutations of presenilin 1. Dehay and colleagues used n