235927 RESULTS

Elizabeth Bowers

VNA Care Network Palliative/Hospice care
Needham , United States

Neurofilament in Blood Foretells Early Onset Alzheimer’s

RESEARCH NEWS 2019-01-21 Research News A paper published online today in Nature Medicine finds that in familial Alzheimer’s disease, blood levels of neurofilament light (NfL) rise 16 years before the predicted age of onset. Scientists led by Mathias Jucker, German Center for ...

PAPER Preische O, Schultz SA, Apel A, Kuhle J, Kaeser SA, Barro C, Gräber S, Kuder-Buletta E, LaFougere C, Laske C, Vöglein J, Levin J, Masters CL, Martins R, Schofield PR, Rossor MN, Graff-Radford NR, Salloway S, Ghetti  B, Ringman JM, Noble JM, Chhatwal J, Goate    AM, Benzinger    TL, Morris JC, Bateman RJ, Wang G, Fagan AM, McDade EM, Gordon    BA, Jucker    M, Dominantly Inherited Alzheimer Network

Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease

Nature Medicine Letters, January 21, 2019

Benjamin Tuck

UK DRI at the University of Cambridge
Cambridge, United Kingdom

Invasion of the Microtubules: Mutant Tau Deforms Neuronal Nuclei

RESEARCH NEWS 2019-01-19 Research News A paper in the January 15 Cell Reports suggests that tauopathies cause defects in nucleocytoplasmic transport. Scientists led by Rick Livesey, University College London, report that mutated tau gives rise to microtubules that prod neuronal ...

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