SEARCH RESULTS

237614 RESULTS

Midlife Peripheral Inflammation May Drive Later Cognitive Decline

RESEARCH NEWS 2019-02-20 Research News A decades-long study of more than 12,000 participants suggests that midlife inflammation drives cognitive decline in old age. Scientists led by Rebecca Gottesman, Johns Hopkins Medicine, Baltimore, report in the February 13 Neurology that ...

PSEN1 G417S

MUTATIONS 73685842 GRCh37 (105) G A PSEN1 Exon 12 Point, Missense Coding Unknown Cotton wool plaques throughout cortex, abundant Aβ deposits in cerebellum and spinal gray matter (one patient). Also, CAA, extensive neuronal loss, astrocytic and microglial markers, ...

PSEN1 T291A

MUTATIONS 73673096 GRCh37 (105) A G PSEN1 Exon 9 Point, Missense Coding Unknown Unknown, patient with 2 PSEN1 mutations (A434T, T291A) had AD pathology with cotton wool plaques, diffuse deposits, and severe amyloid angiopathy T291A Alzheimer's Disease: Unclear ...

PSEN1 S132A

MUTATIONS 73640329 GRCh37 (105) rs200937800 T G PSEN1 Exon 5 Point, Missense Coding Unknown Neuropathology consistent with AD, with severe neocortical Lewy body disease (one case). S132A Dementia with Lewy Bodies: Pathogenic, Alzheimer's Disease: ...

PSEN1 Q222P

MUTATIONS 73659468 GRCh37 (105) A C PSEN1 Exon 7 Point, Missense Coding Unknown Unknown Q222P Alzheimer's Disease: PathogenicAlzheimer's Disease CAG Q CCG P 222 ...

PSEN1 V391G

MUTATIONS PSEN1 73683876 GRCh37 (105) T G Exon 11 Point, Missense Coding Unknown, probable damaging as predicted by SIFT, Poly-Phen-2, and Mutation Taster. Phenotype complicated by family history of extrapyramidal disease with several associated recessive mutations ...

Current Filters

No filters selected

Filter By

DATE RANGE
  • All
  • Past 7 Days
  • Past 30 Days
  • Past 90 Days
  • Past 12 Months
  • Specific Dates
    1. From
      To

TYPE