PAPER Morris JC, Roe CM, Grant EA, Head D, Storandt M, Goate AM, Fagan AM, Holtzman DM, Mintun MA
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PAPER Storandt M, Mintun MA, Head D, Morris JC
Cognitive decline and brain volume loss as signatures of cerebral amyloid-beta peptide deposition identified with Pittsburgh compound B: cognitive decline associated with Abeta deposition.
Arch Neurol. 2009 Dec;66(12):1476-81. PubMed: 20008651PAPER Swistowski A, Zhang Q, Orcholski ME, Crippen D, Vitelli C, Kurakin A, Bredesen DE
Novel mediators of amyloid precursor protein signaling.
J Neurosci. 2009 Dec 16;29(50):15703-12. PubMed: 20016085PAPER Hong JH, Hwang ES, McManus MT, Amsterdam A, Tian Y, Kalmukova R, Mueller E, Benjamin T, Spiegelman BM, Sharp PA, Hopkins N, Yaffe MB
TAZ, a transcriptional modulator of mesenchymal stem cell differentiation.
Science. 2005 Aug 12;309(5737):1074-8. PubMed: 16099986PAPER Kurakin A, Wu S, Bredesen DE
Target-assisted iterative screening of phage surface display cDNA libraries.
Methods Mol Biol. 2004;264:47-60. PubMed: 15020779PAPER Hill EK, Krebs B, Goodall DG, Howlett GJ, Dunstan DE
Shear flow induces amyloid fibril formation.
Biomacromolecules. 2006 Jan;7(1):10-3. PubMed: 16398490PAPER Knowles TP, Waudby CA, Devlin GL, Cohen SI, Aguzzi A, Vendruscolo M, Terentjev EM, Welland ME, Dobson CM
An analytical solution to the kinetics of breakable filament assembly.
Science. 2009 Dec 11;326(5959):1533-7. PubMed: 20007899PAPER Montine TJ, Larson EB
Late-life dementias: does this unyielding global challenge require a broader view?
JAMA. 2009 Dec 16;302(23):2593-4. PubMed: 20009062PAPER Lieb W, Beiser AS, Vasan RS, Tan ZS, Au R, Harris TB, Roubenoff R, Auerbach S, Decarli C, Wolf PA, Seshadri S
Association of plasma leptin levels with incident Alzheimer disease and MRI measures of brain aging.
JAMA. 2009 Dec 16;302(23):2565-72. PubMed: 20009056PAPER Holden KF, Lindquist K, Tylavsky FA, Rosano C, Harris TB, Yaffe K,
Serum leptin level and cognition in the elderly: Findings from the Health ABC Study.
Neurobiol Aging. 2009 Sep;30(9):1483-9. PubMed: 18358569PAPER Narita K, Kosaka H, Okazawa H, Murata T, Wada Y
Relationship between plasma leptin level and brain structure in elderly: a voxel-based morphometric study.
Biol Psychiatry. 2009 Jun 1;65(11):992-4. PubMed: 19026409PAPER Harvey J, Shanley LJ, O'Malley D, Irving AJ
Leptin: a potential cognitive enhancer?
Biochem Soc Trans. 2005 Nov;33(Pt 5):1029-32. PubMed: 16246038PAPER Watts JC, Huo H, Bai Y, Ehsani S, Jeon AH, Won AH, Shi T, Daude N, Lau A, Young R, Xu L, Carlson GA, Williams D, Westaway D, Schmitt-Ulms G
Interactome analyses identify ties of PrP and its mammalian paralogs to oligomannosidic N-glycans and endoplasmic reticulum-derived chaperones.
PLoS Pathog. 2009 Oct;5(10):e1000608. PubMed: 19798432Multi-Paper Alert: More Data That Brain Amyloid Is Bad for You
RESEARCH NEWS 2009-12-18 Research News The December 14 issue of Archives of Neurology features three papers and an editorial from scientists at Washington University in St Louis, Missouri, that, taken together, strengthen the case for using readouts of amyloid in the brain or the
Weight, Weight, Don’t Tell Me—Leptin Lowers AD Risk?
RESEARCH NEWS 2009-12-18 Research News Leptin, the satiety hormone that signals when to say when at big holiday feasts, also seems to guard against Alzheimer disease, a report in this week’s JAMA suggests. In a prospective study of 785 dementia-free seniors, those with blood lept
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