PAPER Guo Q, Bedford MT, Fast W
PAPER Assohou-Luty C, Raijmakers R, Benckhuijsen WE, Stammen-Vogelzangs J, de Ru A, van Veelen PA, Franken KL, Drijfhout JW, Pruijn GJ24594197
PAPER Anzilotti C, Pratesi F, Tommasi C, Migliorini P19540364
COMMENT The termination of this trial is sad news for the Alzheimer patients, but does not surprise me. The termination simply shows that BACE inhibitors need to be given early—as a secondary prevention—to be successful. Thus, clinical trials with BACE inhibitors ...
RESEARCH NEWS 2018-02-23 Research News In 2016, the FDA approved the serotonin-boosting antipsychotic pimavanserin to treat hallucinations and delusions associated with Parkinson’s disease psychosis. Would the drug curb these symptoms in people with Alzheimer’s, a disease with a ...
COMMUNITY NEWS 2018-02-23 Community News A new funding stream will support neurodegeneration research, courtesy of Facebook founder Mark Zuckerberg and pediatrician Priscilla Chan. The couple’s philanthropy, the Chan Zuckerberg Initiative, opened a request for applications for ...
PAPER Bargmann C29300028
COMMUNITY NEWS 2018-02-23 Community News The Alzheimer’s field has lost another pioneer with the passing of Jacques Nunez, who died February 10. For most of his career, Nunez was a biochemist at INSERM in France, where he studied tau and MAP2 in axonal and dendritic growth. He is ...
PAPER Gache Y, Guilleminot J, Ricolfi F, Theiss G, Nunez J1374115
PAPER Nunez J2469170
University of ManchesterManchester, United Kingdom
PAPER Hesse R, von Einem B, Wagner F, Bott P, Schwanzar D, Jackson RJ, Föhr KJ, Lausser L, Kroker KS, Proepper C, Walther P, Kestler HA, Spires-Jones TL, Boeckers T, Rosenbrock H, von Arnim CA
sAPPβ and sAPPα increase structural complexity and E/I input ratio in primary hippocampal neurons and alter Cahomeostasis and CREB1-signaling.Exp Neurol. 2018 Feb 18; PubMed: 29466703
PAPER Lee FJ, Liu F, Pristupa ZB, Niznik HB
Direct binding and functional coupling of α-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis.FASEB J. 2001 Apr;15(6):916-926. PubMed: 29461115
PAPER Raheja R, Regev K, Healy BC, Mazzola MA, Beynon V, von Glehn F, Paul A, Diaz-Cruz C, Gholipour T, Glanz BI, Kivisakk P, Chitnis T, Weiner HL, Berry JD, Gandhi R29466830
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