COMMENT The termination of this trial is sad news for the Alzheimer patients, but does not surprise me. The termination simply shows that BACE inhibitors need to be given early—as a secondary prevention—to be successful. Thus, clinical trials with BACE inhibitors ...
University of ManchesterManchester, United Kingdom
Massachusetts General Hospital, Harvard Medical SchoolBoston, United States
COMMENT Over the past year, the nature of astrocyte diversity has emerged as a hot topic in the field of glial biology, with several papers describing both regional differences and distinct subpopulations in the normal brain (Chai et al., 2017; Morel et al., 2017 ...
COMMENT Aging is associated with marked changes in brain function and is the biggest risk factor for the development of neurodegenerative diseases. Glial cells in the brain, including astrocytes, are the first responders to most types of stress, and thus it is ...
PAPER Morel L, Chiang MS, Higashimori H, Shoneye T, Iyer LK, Yelick J, Tai A, Yang Y28821665
PAPER John Lin CC, Yu K, Hatcher A, Huang TW, Lee HK, Carlson J, Weston MC, Chen F, Zhang Y, Zhu W, Mohila CA, Ahmed N, Patel AJ, Arenkiel BR, Noebels JL, Creighton CJ, Deneen B28166219
Baylor College of MedicineHouston, United States
CONFERENCE 2018-10-25 00:00:00-2018-10-26 00:00:00 London, England, U.K. 25 – 26 October 2018 Scientists from academia and pharma will present their latest research results in the field of PSP, CBD, and related diseases. Sessions include updates from the PSP Genetics Consortium, the brain banks ...
CONFERENCE 2018-04-18 00:00:00-2018-04-18 00:00:00 Sofia, Bulgaria 18 April 2018 Attendance is free, but registration is required. Contact: firstname.lastname@example.org View Conference Website 1 ...
Boston, United States
PAPER Chai H, Diaz-Castro B, Shigetomi E, Monte E, Octeau JC, Yu X, Cohn W, Rajendran PS, Vondriska TM, Whitelegge JP, Coppola G, Khakh BS
Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence.Neuron. 2017 Aug 2;95(3):531-549.e9. Epub 2017 Jul 14 PubMed: 28712653
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