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Eric M. Reiman on Liver Tox Ends Janssen BACE Program

COMMENT While last week’s announcement is disappointing, we believe that BACE inhibitors still hold promise in stopping the accumulation of amyloid and preventing the clinical onset of Alzheimer’s disease—particularly in healthy people who are at increased risk ...

PAPER Marioni RE, Harris SE, Zhang Q, McRae AF, Hagenaars SP, Hill WD, Davies G, Ritchie CW, Gale CR, Starr JM, Goate AM, Porteous DJ, Yang J, Evans KL, Deary IJ, Wray NR, Visscher PM

GWAS on family history of Alzheimer's disease.

Transl Psychiatry. 2018 May 18;8(1):99. PubMed: 29777097

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