221389 RESULTS

Are Reversible Amyloids Behind Liquid-Liquid Phase Separation?

RESEARCH NEWS 2018-02-16 Research News Many proteins involved in neurodegeneration have a penchant to undergo liquid phase separation, where they coalesce into highly concentrated fluid droplets. These dynamic and reversible assemblies have important physiological functions, but ...

Microglial Transcriptome Hints at Shortcomings of AD Model

RESEARCH NEWS 2018-02-16 Research News With the realization that microglia play a key role in neurodegenerative conditions, scientists have profiled their transcription patterns to see how they change during disease. A study published in the January 16 Cell Reports pulls together ...

Can Closed-Loop Brain Stimulation Improve Memory?

RESEARCH NEWS 2018-02-16 Research News Scientists have tried enhancing memory by modulating neurons in the brain, to little success. In the February 6 Nature Communications, researchers led by Michael Kahana and Daniel Rizzuto, University of Pennsylvania, Philadelphia, scored a ...

PAPER Ogaki K, Martens YA, Heckman MG, Koga S, Labbé C, Lorenzo-Betancor O, Wernick AI, Walton RL, Soto AI, Vargas ER, Nielsen HM, Fujioka S, Kanekiyo T, Uitti RJ, van Gerpen JA, Cheshire WP, Wszolek ZK, Low PA, Singer W, Dickson DW, Bu G, Ross OA

Multiple system atrophy and apolipoprotein E.

Mov Disord. 2018 Feb 14; PubMed: 29442376

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