CONFERENCE 2018-04-26 00:00:00-2018-04-27 00:00:00 Lille, France 26 April 2018 to 27 April 2018 View Conference Website 1 ...
RESEARCH NEWS 2018-03-23 Research News Parkinson’s disease comes in many flavors, posing a challenge for researchers who design clinical trials in their search for treatments. Knowing how the disease progresses naturally may better their chance of success. A longitudinal study ...
CONFERENCE 2018-04-26 00:00:00-2018-04-27 00:00:00 Lille, France 26 – 27 April 2018 View Conference Website 1 ...
RESEARCH NEWS 2018-03-23 Research News Neuronal TDP-43 pathology marks most cases of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), but how does a single protein fit with such a wide range of symptoms? Researchers led by Jemeen Sreedharan at King's ...
PAPER Yahalom G, Orlev Y, Cohen OS, Kozlova E, Friedman E, Inzelberg R, Hassin-Baer S24903616
PAPER Deshaies JE, Shkreta L, Moszczynski AJ, Sidibé H, Semmler S, Fouillen A, Bennett ER, Bekenstein U, Destroismaisons L, Toutant J, Delmotte Q, Volkening K, Stabile S, Aulas A, Khalfallah Y, Soreq H, Nanci A, Strong MJ, Chabot B, Vande Velde C
TDP-43 regulates the alternative splicing of hnRNP A1 to yield an aggregation-prone variant in amyotrophic lateral sclerosis.Brain. 2018 Mar 19; PubMed: 29562314
COMMENT The paper by Zhao and colleagues reports that Trem2 is a receptor for Aβ, joining a long list of cell surface Aβ-binding proteins on microglia. The authors argue that Trem2 preferentially interacts with Aβ oligomers, with Kd’s in the nM range. A point of ...
PAPER Abbasi J29536076
Broad InstituteCambridge, United States
PAPER Miya Shaik M, Tamargo IA, Abubakar MB, Kamal MA, Greig NH, Gan SH29561798
PAPER Habib A, Hou H, Mori T, Tian J, Zeng J, Fan S, Giunta B, Sanberg PR, Sawmiller D, Tan J
Human Umbilical Cord Blood Serum-derived α-Secretase: Functional Testing in Alzheimer's Disease Mouse Models.Cell Transplant. 2018 Jan 1;:963689718759473. PubMed: 29560732
PAPER Scoles DR, Pulst SM29560813
PAPER Morrice JR, Gregory-Evans CY, Shaw CA29559645
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