GRANT Friday, February 23, 2018- 16:45 Chan Zuckerberg Initiative $350,000 total costs per year for three years, for a total of $1.05 million (including up to 15 percent indirect costs). Letters of Intent due by 5 p.m. PT on April 3, 2018. CZI Collaborative ...
GRANT Friday, February 23, 2018- 16:30 Chan Zuckerberg Initiative $500,000 total costs per year for five years, for a total of $2.5 million (including up to 15 percent indirect costs). Applications due by 5 p.m. PT on April 17. CZI Ben Barres Early Career ...
COMMENT The termination of this trial is sad news for the Alzheimer patients, but does not surprise me. The termination simply shows that BACE inhibitors need to be given early—as a secondary prevention—to be successful. Thus, clinical trials with BACE inhibitors ...
PAPER Bargmann C29300028
COMMUNITY NEWS 2018-02-23 Community News The Alzheimer’s field has lost another pioneer with the passing of Jacques Nunez, who died February 10. For most of his career, Nunez was a biochemist at INSERM in France, where he studied tau and MAP2 in axonal and dendritic growth. He is ...
PAPER Gache Y, Guilleminot J, Ricolfi F, Theiss G, Nunez J1374115
PAPER Nunez J2469170
University of ManchesterManchester, United Kingdom
PAPER Hesse R, von Einem B, Wagner F, Bott P, Schwanzar D, Jackson RJ, Föhr KJ, Lausser L, Kroker KS, Proepper C, Walther P, Kestler HA, Spires-Jones TL, Boeckers T, Rosenbrock H, von Arnim CA
sAPPβ and sAPPα increase structural complexity and E/I input ratio in primary hippocampal neurons and alter Cahomeostasis and CREB1-signaling.Exp Neurol. 2018 Feb 18; PubMed: 29466703
PAPER Lee FJ, Liu F, Pristupa ZB, Niznik HB
Direct binding and functional coupling of α-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis.FASEB J. 2001 Apr;15(6):916-926. PubMed: 29461115
PAPER Raheja R, Regev K, Healy BC, Mazzola MA, Beynon V, von Glehn F, Paul A, Diaz-Cruz C, Gholipour T, Glanz BI, Kivisakk P, Chitnis T, Weiner HL, Berry JD, Gandhi R29466830
PAPER Bertolin C, Querin G, Bozzoni V, Martinelli I, De Bortoli M, Rampazzo A, Gellera C, Pegoraro E, Sorarù G29464931
PAPER Abdelhak A, Hübers A, Böhm K, Ludolph AC, Kassubek J, Pinkhardt EH29464376
PAPER Spiller KJ, Restrepo CR, Khan T, Dominique MA, Fang TC, Canter RG, Roberts CJ, Miller KR, Ransohoff RM, Trojanowski JQ, Lee VM
Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy.Nat Neurosci. 2018 Feb 20; PubMed: 29463850
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