PAPER Park P, Schachter S, Yaksh T
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PAPER Gwon AR, Park JS, Park JH, Baik SH, Jeong HY, Hyun DH, Park KW, Jo DG
Selenium attenuates A beta production and A beta-induced neuronal death.
Neurosci Lett. 2010 Jan 29;469(3):391-5. PubMed: 20026385PAPER Jin T, Ito Y, Luan X, Dangaria S, Walker C, Allen M, Kulkarni A, Gibson C, Braatz R, Liao X, Diekwisch TG
Elongated polyproline motifs facilitate enamel evolution through matrix subunit compaction.
PLoS Biol. 2009 Dec;7(12):e1000262. PubMed: 20027208PAPER Wang Y, Zhang G, Zhou H, Barakat A, Querfurth H
Opposite effects of low and high doses of Abeta42 on electrical network and neuronal excitability in the rat prefrontal cortex.
PLoS One. 2009;4(12):e8366. PubMed: 20027222PAPER Gaidukov L, Viji RI, Yacobson S, Rosenblat M, Aviram M, Tawfik DS
ApoE induces serum paraoxonase PON1 activity and stability similar to ApoA-I.
Biochemistry. 2010 Jan 26;49(3):532-8. PubMed: 20025294PAPER Passos GF, Figueiredo CP, Prediger RD, Silva KA, Siqueira JM, Duarte FS, Leal PC, Medeiros R, Calixto JB
Involvement of phosphoinositide 3-kinase gamma in the neuro-inflammatory response and cognitive impairments induced by beta-amyloid 1-40 peptide in mice.
Brain Behav Immun. 2010 Mar;24(3):493-501. PubMed: 20025958PAPER Arslan PE, Mulligan VK, Ho S, Chakrabartty A
Conversion of Abeta42 into a folded soluble native-like protein using a semi-random library of amphipathic helices.
J Mol Biol. 2010 Mar 12;396(5):1284-94. PubMed: 20026077PAPER Agrawal R, Mishra B, Tyagi E, Nath C, Shukla R
Effect of curcumin on brain insulin receptors and memory functions in STZ (ICV) induced dementia model of rat.
Pharmacol Res. 2010 Mar;61(3):247-52. PubMed: 20026275PAPER Cairns NJ, Ikonomovic MD, Benzinger T, Storandt M, Fagan AM, Shah A, Schmidt RE, Perry A, Reinwald LT, Carter D, Felton A, Holtzman DM, Mintun MA, Klunk WE, Morris JC
Absence of PIttsburgh Compound B Detection of CerebralAmyloid Beta in a Patient With Clinical, Cognitive, and Cerebrospinal FluidMarkers of Alzheimer Disease.
Arch Neurol. 2009 Dec;66(12):1557-1562. PubMed: 20027238PAPER Rockabrand E, Slepko N, Pantalone A, Nukala VN, Kazantsev A, Marsh JL, Sullivan PG, Steffan JS, Sensi SL, Thompson LM
The first 17 amino acids of Huntingtin modulate its sub-cellular localization, aggregation and effects on calcium homeostasis.
Hum Mol Genet. 2007 Jan 1;16(1):61-77. PubMed: 17135277PAPER Atwal RS, Xia J, Pinchev D, Taylor J, Epand RM, Truant R
Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity.
Hum Mol Genet. 2007 Nov 1;16(21):2600-15. PubMed: 17704510PAPER Thompson LM, Aiken CT, Kaltenbach LS, Agrawal N, Illes K, Khoshnan A, Martinez-Vincente M, Arrasate M, O'Rourke JG, Khashwji H, Lukacsovich T, Zhu YZ, Lau AL, Massey A, Hayden MR, Zeitlin SO, Finkbeiner S, Green KN, Laferla FM, Bates G, Huang L, Patterson PH, Lo DC, Cuervo AM, Marsh JL, Steffan JS
IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome.
J Cell Biol. 2009 Dec 28;187(7):1083-99. PubMed: 20026656Steve Barger on APP Makes a Calcium Connection in Neurons
COMMENT The finding that APP depletion can result in aberrations in calcium-channel function and synaptic function is interesting for reasons beyond the "protein’s normal role in neurons." We reported a little over a year ago that APP is severely deplet
Virgil Muresan on Brain-derived neurotrophic factor reduces amyloidogenic processing through control of SORLA gene expression.
COMMENT We would like to comment on two aspects raised by the interesting paper by Rohe et al. (1), which elegantly shows that BDNF can control the amyloidogenic processing of APP by regulating the expression of SORLA. This pathway of regulation suggests that the
PAPER Reiman EM, Chen K, Caselli RJ, Alexander GE, Bandy D, Adamson JL, Lee W, Cannon A, Stephan EA, Papassotiropoulos A
Cholesterol-related genetic risk scores are associated with hypometabolism in Alzheimer's-affected brain regions.
Neuroimage. 2008 April 1;40(3):1214-21.Current Filters
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