. In vivo detection of amyloid plaques in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):7609-14. PubMed.


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  1. If this works in humans, it will be great for antemortem quantitation of amyloid load.

  2. This method provides a non-invasive method for monitoring plaque load, which can be useful in studying factors that regulate plaque load.

  3. This study suggests that imaging amyloid plaques may be possible in the future. This would have a significant impact on treatment and diagnosis of AD and related diseases.

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This paper appears in the following:


  1. Toward Visualizing Plaques in Vivo