. Transgenic Drosophila expressing human amyloid precursor protein show gamma-secretase activity and a blistered-wing phenotype. Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13703-8. PubMed.


Please login to recommend the paper.


  1. This is an interesting paper as it suggests a function for APP in cell adhesion/signaling. The APP FAD mutations may disturb this function in AD independently of beta A4 generation.

Make a Comment

To make a comment you must login or register.