. TLR2 is a primary receptor for Alzheimer's amyloid β peptide to trigger neuroinflammatory activation. J Immunol. 2012 Feb 1;188(3):1098-107. PubMed.


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  1. This is an important finding that demonstrates that microglial TR2, whose activation can be up- and downregulated by TR1 and TR6, respectively, would be a potential therapeutic target.

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