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Inserm
I have some difficulty to understand this paper. There are no data of bryostatin on APP V717I mutated mice. For the other model, APP(V717I)/PS1 (A246E), the study presents data on mortality, but not on the number of amyloid plaques, nor on the secretion of sAPPalpha and cognition.
Therefore this paper offers many different (and unrelated) stories followed by a unifying conclusion that I have some difficulty to believe.
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