. Targeting BACE1 with siRNAs ameliorates Alzheimer disease neuropathology in a transgenic model. Nat Neurosci. 2005 Oct;8(10):1343-9. PubMed.


Please login to recommend the paper.


  1. Readers should also consult a recent paper from the laboratory of Bart De Strooper and colleagues. Their data "challenge the general idea of BACE1 as a safe drug target..."

Make a Comment

To make a comment you must login or register.