. Stress-induced hyperphosphorylation of tau in the mouse brain. FEBS Lett. 2003 Jan 30;535(1-3):183-9. PubMed.


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  1. The abstract for this paper does not adequately describe the findings of this work or their implications. I recommend reading the full paper. Essentially, the work suggests that tau hyperphosphorylation is not the work of a single protein kinase or phosphatase, but is likely to involve several different enzymes, their levels or activity, or their subcellular distribution, each of which may be influenced by a wide variety of cellular or metabolic factors.

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