. Side chain-dependent stacking modulates tau filament structure. J Biol Chem. 2006 Dec 8;281(49):37820-7. PubMed.


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  1. Parallel, in-register β strand packing is turning out to be a common motif in amyloid fibrils of many diseases. This leads to the stacking of amino acid side chains of the same type as zippers runing up and down the β sheet.

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