. Secreted glypican binds to the amyloid precursor protein of Alzheimer's disease (APP) and inhibits APP-induced neurite outgrowth. J Biol Chem. 1996 Dec 6;271(49):31215-21. PubMed.


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  1. This paper is important because it provides further evidence for the neuroprotective role of APP. Mechanisms of neurite outgrowth are important areas of research in developing treatments for AD.

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