. The role of the amyloid protein precursor (APP) in Alzheimer's disease: does the normal function of APP explain the topography of neurodegeneration?. Neurochem Res. 1998 May;23(5):795-806. PubMed.


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  1. Small presents a theoretical treatise aimed at explaining how the neuropathology of AD can be explained in terms of an amyloid disturbance. The hypothesis presented is rather weak and not supported by any hard data.

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