Sofola OA, Jin P, Qin Y, Duan R, Liu H, de Haro M, Nelson DL, Botas J. RNA-binding proteins hnRNP A2/B1 and CUGBP1 suppress fragile X CGG premutation repeat-induced neurodegeneration in a Drosophila model of FXTAS. Neuron. 2007 Aug 16;55(4):565-71. PubMed.

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  1. This is an interesting study implicating aberrant binding of RNA-binding proteins to CGG repeats in mechanisms of neurodegeneration.

    View all comments by John Trojanowski

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