. PS2APP transgenic mice, coexpressing hPS2mut and hAPPswe, show age-related cognitive deficits associated with discrete brain amyloid deposition and inflammation. J Neurosci. 2003 Oct 1;23(26):8989-9003. PubMed.


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Research Models

  1. APPSwe
  2. PS2(N141I)
  3. PS2APP (PS2(N141I) x APPswe)
  4. PS2APP


  1. PSEN2 N141I