. Prostaglandins act as neurotoxin for differentiated neuroblastoma cells in culture and increase levels of ubiquitin and beta-amyloid. In Vitro Cell Dev Biol Anim. 1998 Mar;34(3):265-74. PubMed.


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  1. This is an interesting paper. It shows that besides the FAD mutation, cellular Abeta can increase in response to other toxic conditions including neuronal stress. That has implications on the putative role of amyloid in AD.

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