. Presenilin-1 mutations increase levels of ryanodine receptors and calcium release in PC12 cells and cortical neurons. J Biol Chem. 2000 Jun 16;275(24):18195-200. PubMed.


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  1. It is curious how PS-1 dependent ER-stress is related with release of cellular Ca2+ in the present clear system.

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  1. Perplexing Presenilins: New Evidence for Calcium Leak Channels