. Presenilin 1 intronic polymorphism is not associated with Alzheimer type neuropathological changes or sporadic Alzheimer's disease. J Neurol Neurosurg Psychiatry. 1998 Apr;64(4):548-51. PubMed.


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  1. This study also shows the absence of relationship between PS-1 polymorphophism and non-familial sporadic AD patients. Negative results are as interesting as positive ones.

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