Sodeyama N, Itoh Y, Suematsu N, Matsushita M, Otomo E, Mizusawa H, Yamada M. Presenilin 1 intronic polymorphism is not associated with Alzheimer type neuropathological changes or sporadic Alzheimer's disease. J Neurol Neurosurg Psychiatry. 1998 Apr;64(4):548-51. PubMed.
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Osaka City University Medical School
This study also shows the absence of relationship between PS-1 polymorphophism and non-familial sporadic AD patients. Negative results are as interesting as positive ones.
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