. Phosphatidylinositol and inositol involvement in Alzheimer amyloid-beta fibril growth and arrest. J Mol Biol. 1998 Apr 24;278(1):183-94. PubMed.


Please login to recommend the paper.


  1. At neutral pH, PI influences amyloidosis of in vitro Ab1-42 but not Ab1-40. This may be relevant with the presence of diffuse plaque formation.

  2. This is a nice paper because it examines the role of lipids in amyloid formation. Such a role was already indicated by several laboratories. There are good evidence indications that the first seeds of amyloid fibrils may form on membranes.

Make a Comment

To make a comment you must login or register.

This paper appears in the following:


  1. Aβ Busters and Other Ploys Show Promise for Treating Neurodegeneration